多层螺旋CT肺部磨玻璃结节表现对早期肺腺癌的诊断价值

Diagnostic Value of Multislice Spiral CT Findings of Pulmonary Ground Glass Nodules on Early Lung Adenocarcinoma

目的:分析肺部磨玻璃结节多层螺旋CT影像学表现对早期肺腺癌的诊断价值。方法:回顾性分析2019年1月1日-2021年12月31日江苏省沭阳中兴医院收治的51例肺部磨玻璃结节患者的多层螺旋CT检查资料,患者均经手术病理检查确诊为早期肺腺癌。按病理类型的不同分为浸润前病变组(12例)、微浸润性腺癌组(25例)、浸润性腺癌组(14例)。分析早期肺腺癌不同病理分型多层螺旋CT检查影像学表现的差异性。结果:浸润前病变组的血管特征、胸膜凹陷征与微浸润性腺癌组比较,差异有统计学意义(P<0.05);浸润前病变组的空气支气管征、瘤-肺界面、毛刺征、分叶征、血管特征、胸膜凹陷征情况与浸润性腺癌组比较,差异有统计学意义(P<0.05);微浸润性腺癌组的病灶形态、空气支气管征、瘤-肺界面、毛刺征、分叶征、胸膜凹陷征情况与浸润性腺癌组比较,差异有统计学意义(P<0.05)。结论:对多层螺旋CT肺部磨玻璃结节表现进行评估能够有效区分浸润前病变、微浸性润腺癌、浸润性腺癌,临床可根据早期肺腺癌的不同病理分型制定针对性治疗措施。

Objective:To analyze the diagnostic value of multislice spiral CT imaging findings of pulmonary ground glass nodules on early lung adenocarcinoma.Methods:Multislice spiral CT examination data of 51 patients with pulmonary ground glass nodules who were admitted to Jiangsu Province Shuyang Zhongxing Hospital from January 1,2019 to December 31,2021 were retrospectively analyzed,and all the patients were diagnosed as early lung adenocarcinoma by surgical pathological examination.According to the different pathological types,they were divided into pre-invasive lesions group(n=12),minimally invasive adenocarcinoma group(n=25),and invasive adenocarcinoma group(n=14).The differential imaging performance of multislice spiral CT in different pathological types of early lung adenocarcinoma was analyzed.Results:There were significant differences in the characteristics of blood vessels and pleural indentation sign between the pre-invasive lesions group and the minimally invasive adenocarcinoma group(P<0.05).There were significant differences in air bronchogram sign,tumor-lung interface,spicule sign,lobulation sign,vascular feature,and pleural indentation sign between the pre-invasive lesions group and the invasive adenocarcinoma group(P<0.05).There were significant differences in focus morphology,air bronchogram sign,tumor-lung interface,spicule sign,lobulation sign,and pleural indentation sign between the minimally invasive adenocarcinoma group and the invasive adenocarcinoma group(P<0.05).Conclusion:Evaluation of the pulmonary ground glass nodules in multislice spiral CT findings can effectively distinguish pre-invasive lesions,minimally invasive adenocarcinoma,and invasive adenocarcinoma.Targeted therapeutic measures can be formulated clinically according to the different pathological types of early lung adenocarcinoma.