升陷汤联合以运动为主的家庭心脏康复在冠心病患者中的应用效果观察

Application Effect Observation of Shengxian Decoction Combined with Exercise-Based Home Cardiac Rehabilitation in Patients with Coronary Heart Disease

目的:探讨升陷汤联合以运动为主的家庭心脏康复在冠心病患者中的应用效果。方法:选取2018年11月-2019年4月北京市海淀区羊坊店社区卫生服务中心收治的110例稳定性冠心病患者作为研究对象,根据随机数字表法分为干预组与对照组,各55例。对照组实施以运动为主的家庭心脏康复,干预组在对照组基础上给予升陷汤加减进行治疗,比较两组血脂指标、情绪评分、生活质量评分、6分钟步行距离(6MWD)及不良反应发生情况。结果:治疗前,两组血清总胆固醇(TC)、甘油三酯(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)指标比较,差异无统计学意义(P>0.05)。治疗后,两组TC、LDL-C指标均低于治疗前,且干预组低于对照组,差异有统计学意义(P<0.05)。治疗后,干预组TG低于治疗前,且低于对照组,差异有统计学意义(P<0.05);对照组治疗前后TG比较,差异无统计学意义(P>0.05)。治疗前后,两组HDL-C比较,差异无统计学意义(P>0.05)。治疗前,两组广泛性焦虑障碍量表(GAD-7)、抑郁症筛查量表(PHQ-9)、生活质量评定量表(SF-12)评分及6MWD比较,差异无统计学意义(P>0.05);治疗后,两组GAD-7、PHQ-9、SF-12评分及6MWD均优于治疗前,且干预组优于对照组,差异有统计学意义(P<0.05)。两组均未发生不良反应。结论:升陷汤联合以运动为主的家庭心脏康复能够改善冠心病患者血脂水平,提高患者运动耐力,改善其心理状态,提高其生存质量。

Objective:To explore the application effect of Shengxian decoction combined with exercise-based home cardiac rehabilitation in patients with coronary heart disease.Methods:From November 2018 to April 2019,110 patients with stable coronary heart disease admitted to Yangfangdian Community Health Service Center in Haidian District of Beijing were selected as the study subjects,and they were divided into intervention group and control group according to the random number table method,with 55 cases in each group.The control group underwent exercise-based home cardiac rehabilitation,and the intervention group was treated with Shengxian decoction on the basis of control group.The blood lipid indexes,mood score,quality of life score,6-minute walking distance (6MWD) and adverse reactions of the two groups were compared.Results:Before treatment,there was no significant difference in serum total cholesterol (TC),triglycerides (TG),high-density lipoprotein cholesterol (HDL-C),and low-density lipoprotein cholesterol (LDL-C) between the two groups (P>0.05).After treatment,the TC and LDL-C indexes of the two groups were lower than those before treatment,and the intervention group was lower than the control group,and the difference was statistically significant (P<0.05).After treatment,the TG in the intervention group was lower than that before treatment and lower than that in the control group,and the difference was statistically significant (P<0.05).There was no significant difference in TG before and after treatment in the control group (P>0.05).There was no significant difference in HDL-C between the two groups before and after treatment (P>0.05).Before treatment,there were no significant differences between the two groups in the generalized anxiety disorder scale (GAD-7),depression screening scale (PHQ-9),quality of life rating scale (SF-12) and 6MWD(P>0.05).After treatment,the GAD-7,PHQ-9,SF-12 scores and 6MWD of the two groups were better than those before treatment,and the intervention group was better than the control group,and the difference was statistically significant (P<0.05).There were no adverse reactions in either group.Conclusion:The Shengxian decoction combined with exercise-based home cardiac rehabilitation can improve the blood lipid level,enhance the exercise tolerance,improve the psychological state and quality of life in patients with coronary heart disease.