大脑海马沟立体定位数据集的构建及投影回归分析

Construction of stereotactic localization data set and projection regression analysis of hippocampal sulcus

目的:构建大脑海马沟基于连合间径(AC-PC)定位体系中的立体定位数据集及其平面投影回归方程。方法:将30名健康成年人颅脑横断层MRI数据经格式转化导入Photoshop CS软件包,经过严格的图像配准,建立以AC-PC中点为原点的三维立体坐标系,获取海马沟在脑MRI冠状面图像上的三维立体坐标值,以海马沟的最外侧点为起始点,记录该点坐标的X、Z值,其在软件的信息面板中直接显示,Y值为该图像所在层面与AC-PC层面间隔的层数乘以层间距,所有取样点坐标值构成大脑海马沟在三维坐标系中的立体定位数据集。利用SPSS25.0对所获取的取样点数据进行统计处理,求解其投影回归方程。结果:成功构建大脑海马沟在在三维坐标系中的立体定位数据集及其在横断、矢状、冠状面上的投影回归方程。冠状面上Z值对X值回归方程,右侧:Z=-46.379-0.302X(P<0.05),左侧:Z=-49.512+0.425X(P<0.05);横断面上Y值对X值回归方程,右侧:Y=-0.380-0.198X(P>0.05),左侧:Y=2.982+0.106X(P>0.05);矢状面上Z值对Y值回归方程,右侧Z=-38.501+0.416Y(P<0.01),左侧:Z=-36.793+0.326Y(P<0.01)。结论:大脑海马沟横断、冠状及矢状面的三维坐标值间的相关关系较不密切。构建的海马沟立体定位数据集可为海马区域病灶定位及该区域脑立体定向手术的靶点确定、手术路径规划提供精确的影像解剖学数据。

Objective:To construct the stereotatic localization data set and its plane projection regression equation of the hippocampal sulcus based on the AC-PC localization system.Methods:The transverse tomography data of 30 healthy adults were imported into Photoshop CS software package by format transformation.After strict image registration,a three-dimensional sitting system with AC-PC midpoint as the origin was established to obtain the three-dimensional coordinate values of hippocampal sulcus in the coronal plane images of brain.Taking the outermost point of the hippocampal sulcus as the starting point,record the X-value and Z-value,which were directly displayed in the information panel of the software,and the Y-value was the product of the number of layers between the image layer and AC-PC plane and interlayer spacing.The stereotactic data set of the hippocampal sulcus in a three-dimensional coordinate system were constituted by all the coordinate values of sample points.The SPSS25.0 software was used to calculate the obtained sampling point data,and solve the projection regression equation.Results:The stereotaxic dataset of the hippocampal sulcus in the three-dimensional coordinate system and its projection regression equation on the transverse,sagittal and coronal planes were successfully constructed.On the right side of the regression equation of Z-value to X-value on the coronal plane:Z=-46.379-0.302X(P<0.05),on the left side:Z=-49.512+0.425X(P<0.05).On the right side of the regression equation of Y-value to X-value on the transverse plane:Y=-0.380-0.198X(P>0.05),on the left side:Y=2.982+0.106X(P>0.05).On the right side of the regression equation of Z-value to Y-value on the sagittal plane:Z=-38.501+0.416Y(P<0.01),on the left side:Z=-36.793+0.326Y(P<0.01).Conclusions:The correlation among the three-dimensional coordinate values of the transverse,coronal and sagittal plane of the hippocampal sulcus of the brain is not close.The stereotactic localization data set of the hippocampal sulcus provides accurate image anatomical data for the localization of lesions,the target determination and surgical path planning of stereotactic surgery in the hippocampal region.