急性胰腺炎镇痛管理现状

Current status of analgesic management in acute pancreatitis

疼痛是急性胰腺炎的典型临床症状,对诊断和治疗极为重要,目前临床上常规使用的镇痛药物包括阿片类药物和非甾体类抗炎药(non-steroid anti-inflammatory drugs,NSAIDs),但就何种药物更安全有效一直存在争议,更多的是依赖于临床医师的经验用药,目前鲜见针对急性胰腺炎镇痛治疗的共识和指南。本文对目前急性胰腺炎常规镇痛药物的选择、营养管理、硬膜外麻醉以及新兴的镇痛策略作一概述。

Pain is a typical clinical symptom of acute pancreatitis and is extremely important for its diagnosis and treatment.Opioids and non-steroid anti-inflammatory drugs(NSAIDs)are routinely used clinically,but there has been controversy over which drugs are safer and the choice is more dependent on clinicians′experience.What′s more,there are few consensus and guidelines for acute pancreatitis analgesia.This article reviewed the current selection of conventional analgesic drugs for acute pancreatitis,nutritional management,epidural anesthesia,and emerging analgesic strategies.