2015—2019年云南省居民肝癌死亡趋势及寿命损失分析

Analysis of death trend and life loss of liver cancer in Yunnan Province,2015-2019

目的了解2015―2019年云南省居民肝癌的死亡水平、变化趋势及寿命损失情况,为当地制定科学的防制措施提供依据。方法通过《人口死亡信息登记管理系统》获取云南省2015―2019年的肝癌死因监测数据,利用Stata 16软件和Excel 2019软件计算肝癌死亡和寿命损失相关指标,并用Joinpoint 4.9.0软件分析肝癌死亡和寿命损失的变化趋势,采用统计描述方法对云南省肝癌的死亡水平和寿命损失情况进行流行病学描述。结果2015―2019年云南省肝癌死亡累计报告30912例,平均死亡年龄为(61.76±13.81)岁,标化死亡率(standardized mortality rate,SMR)从2015年的12.40/10万上升到2019年的14.10/10万,男性死亡率均高于女性,农村高于城市。云南省肝癌死亡率随年龄增长而增加,男性35岁死亡趋势开始快速增加。2015―2019年因肝癌死亡导致的潜在减寿年数(potential years of life lost,PYLL)为256380人年,潜在减寿年率(potential years of life lost rate,PYLLR)为1.08‰;标化潜在减寿年数(standardized potential years of life loss,SPYLL)为266962人年;标化潜在减寿年率(standardized potential years of life loss rate,SPYLLR)为1.12‰;男性的寿命损失高于女性;农村的寿命损失高于城市。结论2015―2019年云南省肝癌粗死亡率(crude death rate,CDR)和寿命损失呈上升趋势,男性和农村居民是高危人群,今后须加强对男性的早期体检,农村地区须投入更多的医疗资源,向全社会倡导合理膳食、体育锻炼等健康的生活方式,做好肝癌的早期预防工作。

Objective To understand the level of death,changing trends and life expectancy loss of liver cancer among Yunnan residents from 2015 to 2019,and to provide a basis for the development of local scientific prevention and control measures.Methods The cause of death surveillance data of liver cancer in Yunnan Province from 2015 to 2019 were obtained through the Population Death Information Registration Management System.The epidemiological description of the level of death and life expectancy loss of liver cancer in Yunnan Province was performed by Stata16 and Excel 2019 software to calculate the indicators related to liver cancer death and life expectancy loss.And the trend of liver cancer death and life expectancy loss was analyzed by Joinpoint software.Results From 2015 to 2019,30912 cumulative liver cancer deaths were reported in Yunnan Province,with an average age of death of(61.76±13.81)years.And the standardized mortality rate increased from 12.40/100000 in 2015 to 14.10/100000 in 2019,with both male mortality rates were higher than female,and rural mortality rates were higher than urban.The mortality rate of liver cancer in Yunnan Province increased with age,and the trend of death begins to increase rapidly around the age of 35 for male.The potential years of life lost due to death from liver cancer from 2015 to 2019 was 256380 person-years,with a potential life loss rate of 1.08 per 1000.The standardized potential years of life lost was 266962 person-years,with a standardized potential life loss rate of 1.12 per 1000,with higher life loss in male than in female and higher life loss in rural than in urban areas.Conclusions The crude mortality rate and life expectancy loss of liver cancer in Yunnan Province from 2015 to 2019 are on the rise.And male and rural residents are the high-risk groups,so we need to strengthen early medical checkups for male in the future,and invest more medical resources in rural areas to advocate healthy lifestyles such as reasonable diet and physical exercise to the whole society for early prevention of liver cancer.