马术辅助干预对孤独症患者治疗效果的Meta分析

Meta-analysis of the effects of equestrian assisted intervention on autism patients

目的:采用Meta分析马术辅助干预(EAI)对孤独症(ASD)患者的治疗效果。方法:计算机检索知网、万方、维普、PubMed、The Cochrane Library、Medline、Embase等数据库,检索文献的发表时间均为建库至2022年5月20日,由2位评价员对符合纳入标准的文献采用Cochrane风险偏倚评估表进行质量评估。对纳入的文献进行Meta分析,研究结果包括异常行为检查量表-社区版(ABC-C)、社会反应量表(SRS)、语言成绩单系统分析(SALT)、文兰适应行为量表(VABS)等,用标准化均数差(SWD)和加权均数差(WMD)评定疗效,并对异质性进行检验,采用Revman5.3软件进行Meta分析。结果:共纳入9篇文献进行Meta分析,其中中文1篇,英文8篇,共396例。Meta分析结果显示ABC-C量表中易怒子量表(MD=-3.89,95%CI-6.42~-1.35,P=0.003)、多动子量表(MD=-3.63,95%CI-6.41~-0.86,P=0.01)和SRS量表(MD=-1.39,95%CI-2.11~-0.67,P=0.0002)得分均优于对照组。结果表明,试验组与对照组结果差异具有统计学意义,即EAI干预ASD患者具有较高的有效性,尤其是在改善ASD患者易怒、多动等精神障碍问题以及提高其社交和社会能力方面具有显著效果。结论:基于Meta分析结果,EAI干预在改善ASD儿童易怒、多动等精神障碍问题以及提高社交和社会能力方面具有一定可行性和有效性。

Objective:To meta-analyze the therapeutic effect of equestrian assisted intervention(EAI)on autism(ASD)patients.Method:Computer retrieval was conducted on CNKI,Wanfang,VIP,PubMed,The Cochrane Library,Medline,Embase and other databases.The publication time of literature retrieval was from the establishment of the database to May 20,2022.The quality of the literatures meeting the inclusion criteria was assessed using Cochrane risk bias assessment table by 2 reviewers.A meta-analysis was performed on the included literature.The results included abnormal Behavior Checklist-Community Edition(ABC-C),Social Response Scale(SRS),Language report Card System analysis(SALT),Vineland Adaptive Behavior Scale(VABS),etc.The efficacy was evaluated by standardized mean difference(SWD)and weighted mean difference(WMD).Heterogeneity was examined and meta-analysis was performed using Revman5.3 software.Results:A total of 9 literatures were included for meta-analysis,including 1 in Chinese and 8 in English,with a total of 396 cases.The results of meta-analysis showed that in the experimental group,the scores of ABC-C Irritable subscale(MD=-3.89,95%CI-6.42~-1.35,P=0.003),hyperactin subscale(MD=-3.63,95%CI-6.41~-0.86,P=0.01)and SRS scale(MD=-1.39,95%CI-2.11-0.67,P=0.0002)were better than the control group.The results showed that there was a statistically significant difference between the experimental group and the control group,that is,the intervention of EAI in patients with ASD has a high effectiveness,especially in improving the irritability,hyperactivity and other mental disorders of patients with ASD,and improving their social and social ability.Conclusion:Based on the results of metaanalysis,EAI intervention has certain feasibility and effectiveness in improving irritability,hyperactivity and other mental disorders in children with ASD,as well as improving social and social ability.