摘要
目的:观察四逆散联合马来酸咪达唑仑片治疗睡眠障碍的临床疗效。方法:选取睡眠障碍患者80例,随机分为对照组和研究组各40例。对照组采用马来酸咪达唑仑片治疗,研究组采用四逆散联合马来酸咪达唑仑片治疗。比较2组临床疗效,2组治疗前后匹兹堡睡眠质量指数(PSQI)评分及简易生活质量量表(SF-36)评分。结果:研究组总有效率为95.0%,对照组为77.5%,2组比较,差异有统计学意义(P<0.05)。治疗前,2组PSQI量表中主观睡眠质量、睡眠潜伏期、睡眠效率、睡眠时间、睡眠紊乱累加问题、应用睡眠药物、日间功能紊乱等项目评分比较,差异无统计学意义(P>0.05);治疗后,2组上述各项评分均较治疗前降低(P<0.05),且研究组各项评分均低于对照组(P<0.05)。治疗前,2组SF-36量表中情感职能、躯体疼痛、精神健康、生理职能、社会功能、生理功能、活力、总体健康等各项评分比较,差异无统计学意义(P>0.05);治疗后,2组上述各项生活质量指标评分均较治疗前提高(P<0.05),且研究组上述各项评分均高于对照组(P<0.05)。结论:四逆散联合马来酸咪达唑仑片治疗失眠障碍可提高临床疗效,有效改善患者的睡眠质量及生活质量。
Objective:To observe the clinical effect of the therapy of Sini Powder combined with Midazolam Maleate Tablets for sleep disorders.Methods:A total of 80 cases of sleep disorders were selected and divided into the control group and the study group,with 40 cases in each group.The control group was given Midazolam Maleate Tablets for treatment,and the control group was treated with Sini Powder combined with Midazolam Maleate Tablets.The clinical effects in both groups as well as the sleep quality valuated by Pittsburgh Sleep Quality Index(PSQI)and Short from 36 Questionnaire(SF-36)scores before and after treatment were compared.Results:The total effective rate was 95.0%in the study group,higher than that of 77.5%in the control group,the difference being significant(P<0.05).Before treatment,there was no significant difference being fund in the comparisons of scores of PSQI scale,including subjective sleep quality,sleep latency,sleep efficiency,sleep time,additive problems of sleep disturbance,sleep medicine taking and daytime function disorders,between the two groups(P>0.05);after treatment,the above scores in both groups were decreased when compared with those before treatment(P<0.05),and the above scores in the study group were lower than those in the control group(P<0.05).Before treatment,there was no significant difference being found in the comparisons of the scores of SF-36,including emotional function,physical pain,mental health,physiological function,social function,physiological function,activity,general health,between the two groups(P>0.05);after treatment,the above scores in both groups were increased when compared with those before treatment(P<0.05),and the above scores in the study group were higher than those in the control group(P<0.05).Conclusion:The therapy of Sini Powder combined with Midazolam Maleate Tablets for sleep disorders can improve the clinical effect and effectively enhance the sleep quality and the quality of life of patients.
作者
郭孟凡
刘爱红
李瑞艳
尹小伟
GUO Mengfan;LIU Aihong;LI Ruiyan;YIN Xiaowei
出处
《新中医》
CAS
2023年第2期10-13,共4页
New Chinese Medicine