行气活血化瘀汤联合康复锻炼治疗腰椎间盘突出症临床研究

Clinical Study on Xingqi Huoxue Huayu Decoction Combined with Rehabilitation Exercise for Lumbar Disc Herniation

目的:观察行气活血化瘀汤联合康复锻炼治疗腰椎间盘突出症(LDH)的临床疗效。方法:选取70例LDH患者,按随机数字表法分为对照组和观察组各35例。对照组给予常规西药治疗,观察组在对照组基础上给予行气活血化瘀汤联合康复锻炼。比较2组临床疗效、中医证候评分、腰椎功能、疼痛程度及炎症反应。结果:观察组总有效率为91.43%,高于对照组68.57%(P<0.05)。治疗后,2组各项中医证候评分较治疗前降低(P<0.05),且观察组各项中医证候评分低于对照组(P<0.05)。治疗后,2组日本骨科协会腰痛评价评价量表(JOA)评分较治疗前升高,Oswestry功能障碍指数(ODI)、视觉模拟量表(VAS)评分较治疗前降低(P<0.05);且观察组JOA评分高于对照组,ODI、VAS评分低于对照组(P<0.05)。治疗后,2组TNF-α、IL-1β水平较治疗前降低(P<0.05);且观察组TNF-α、IL-1β水平低于对照组(P<0.05)。结论:行气活血化瘀汤联合康复锻炼治疗LDH的康复效果显著,可缓解患者临床症状,改善腰椎功能,缓解疼痛感,减轻炎症反应,有利于促进病情康复。

Objective:To observe the clinical effect of the therapy of Xingqi Huoxue Huayu Decoction combined with rehabilitation exercise for lumbar disc herniation(LDH). Methods:A total of 70 patients with LDH were selected and divided into the control group and the observation group according to the random number table method,with 35 cases in each group. The control group was treated with routine western medicine, and the observation group was additionally treated with Xingqi Huoxue Huayu Decoction combined with rehabilitation exercise based on the treatment of the control group. The clinical effects,traditional Chinese medicine(TCM) syndrome scores, lumbar function, degree of pain and inflammatory responses in the two groups were compared. Results: The total effective rate was 91.43% in the observation group,higher than that of 68.57% in the control group(P<0.05). After treatment,each TCM syndrome score in the two groups was decreased when compared with that before treatment(P<0.05),and each TCM syndrome score in the observation group was lower than that in the control group(P<0.05).After treatment,the scores of Japanese Orthopaedic Association(JOA) in the two groups were increased when compared with those before treatment,and the scores of Oswestry Disability Index(ODI) and Visual Analogue Scale(VAS) were decreased(P<0.05);the score of JOA in the observation group was higher,and the scores of ODI and VAS in the observation group were lower than those in the control group(P<0.05). After treatment,the levels of TNF-α and IL-1β in the two groups were decreased when compared with those before treatment(P<0.05);the above levels in the observation group were lower than those in the control group(P<0.05). Conclusion: The therapy of Xingqi Huoxue Huayu Decoction combined with rehabilitation exercise has a significant rehabilitation effect on LDH, which can alleviate the clinical symptoms of patients, improve lumbar function, relieve pain, reduce inflammatory responses, and is good for promoting recovery.