口服抗凝药物在心房颤动特殊人群中的应用研究进展

Research progress on the application of oral anticoagulants in special populations with atrial fibrillation

对高卒中风险的房颤患者进行抗凝治疗,是被相关专科医师熟知并应用于临床的实践操作。然而,部分患者存在如高龄,合并有急性缺血性卒中、与口服抗凝药物相关的颅内出血、胃肠道出血等特殊情况,此时进行抗凝治疗的有效性和安全性尚有争议。作者就结合上述特殊人群的抗凝治疗研究进展进行了综述。

Anticoagulant therapy for the patients with atrial fibrillation at a high risk of stroke is a practical operation that is well known by relevant specialists and applied in clinic.However,some patients have special conditions such as advanced age,acute ischemic stroke,intracranial hemorrhage related to oral anticoagulants and gastrointestinal hemorrhage,etc.The effectiveness and safety of anticoagulant therapy at this time are still controversial.The author reviewed the research progress of anticoagulant therapy combined with the above special populations.