氧驱动雾化吸入与空气压缩泵雾化吸入在重症脑梗死气管切开术后患者中的临床效果对比

Comparison on clinical effect of oxygen driven atomization inhalation and air compression pump atomization inhalation in patients with severe cerebral infarction after tracheotomy

目的 比较氧驱动雾化吸入与空气压缩泵雾化吸入在重症脑梗死气管切开术后患者中的临床效果。方法 90例重症脑梗死气管切开术后患者,按照雾化吸入方式不同分为治疗组和对照组,每组45例。治疗组采用氧驱动雾化吸入治疗,对照组采用空气压缩泵雾化吸入治疗。比较两组患者气道湿化效果、痰液排出情况、气道并发症发生情况。结果 治疗后7 d,治疗组气道湿化满意42例(93.33%),不足2例(4.44%),过量1例(2.22%);对照组气道湿化满意31例(68.89%),不足7例(15.56%),过量7例(15.56%)。治疗组患者气道湿化满意率高于对照组,差异具有统计学意义(P<0.05)。治疗组患者吸痰次数(7.21±2.12)次/d少于对照组的(14.35±3.23)次/d,吸痰量(89.23±6.31)ml/d多于对照组的(80.62±7.53)ml/d,差异均具有统计学意义(P<0.05)。治疗组刺激性咳嗽发生率17.78%、痰痂形成率11.11%、气道黏膜出血发生率8.89%均低于对照组的57.78%、33.33%、44.44%,差异均具有统计学意义(P<0.05)。结论 在重症脑梗死气管切开术后患者治疗中,氧驱动雾化吸入相较空气压缩泵雾化吸入临床效果更好、安全性更高。

Objective To compare the clinical effect of oxygen driven atomization inhalation and air compression pump atomization inhalation in patients with severe cerebral infarction after tracheotomy.Methods A total of 90 patients with severe cerebral infarction after tracheotomy were divided into treatment group and control group according to the different atomization inhalation methods, with 45 cases in each group.The treatment group used oxygen-driven atomization inhalation, and the control group used air compression pump atomization inhalation. The airway humidification effect, sputum excretion, and occurrence of airway complications were compared between the two groups. Results At 7 d after treatment, in the treatment group,the airway humidification was satisfactory in 42 cases(93.33%), inadequate in 2 cases(4.44%) and excessive in 1 case(2.22%);in the control group, the airway humidification was satisfactory in 31 cases(68.89%), inadequate in 7 cases(15.56%) and excessive in 7 cases(15.56%). Patients in the treatment group had better satisfaction rate of airway humidification than the control group, and the difference was statistically significant(P<0.05). The number of aspirations(7.21±2.12) times/d in the treatment group was less than(14.35±3.23) times/d in the control group, and the amount of aspiration(89.23±6.31) ml/d was more than(80.62±7.53) ml/d in the control group,and the differences were statistically significant(P<0.05). The incidence of irritant cough, sputum scab formation and airway mucosal bleeding were 17.78%, 11.11% and 8.89% in the treatment group, which were lower than 57.78%, 33.33% and 44.44% in the control group, and the differences were all statistically significant(P<0.05).Conclusion oxygen driven atomization inhalation is more effective and safer than air compression pump atomization inhalation for patients with severe cerebral infarction after tracheotomy.