睾丸鞘膜恶性间皮瘤的诊疗进展

Diagnosis and treatment progress of malignant mesothelioma of the tunica vaginalis testis

睾丸鞘膜恶性间皮瘤(MMTVT)是一种罕见的肿瘤,目前其流行病学、发病机制、诊断手段选择、治疗方式以及预后等方面还存在着较多争议。石棉暴露、电离辐射、染色体异常等是MMTVT的危险因素,免疫组织化学染色、超声检查、电子显微镜等可用于诊断,积极手术是治疗MMTVT的主要手段。腔镜外科和多学科诊疗(MDT)模式的发展以及肿瘤靶向、免疫治疗时代的到来,将会为MMTVT患者带来更多的获益。

Malignant mesothelioma of the tunica vaginalis testis(MMTVT) is a rare tumor.At present, there are still many disputes in its epidemiology, pathogenesis, selection of diagnostic methods, treatment and prognosis.Asbestos exposure, ionizing radiation and chromosome abnormalities are the risk factors of MMTVT.Immunohistochemistry, ultrasonography and electron microscope can be used for the diagnosis and aggressive surgery is the main treatment method.The development of endoscopic surgery, multi-disciplinary treatment(MDT),tumor targeted therapy and immunotherapy will bring more benefits to MMTVT patients.