谢昌仁运用养阴活血祛痰法预防中风的理论探微

Theoretical exploration of Xie Changren′ s method of nourishing yin,activating blood,and dispelling phlegm to prevent stroke

中风是目前中老年容易发生的脑血管疾病之一,预防对其至关重要。谢昌仁为国家级名中医,谢老博采众方,承古拓新,主张证型应执简驭繁,用药要有方守方,灵活加减,临床防治脑血管病效果显著。谢老强调在临床上,中风的预防至关重要,因中风病多为本虚标实,肝肾亏虚为本,下元亏虚而内风生,风火相煽,加之痰湿壅盛,瘀血阻滞,痰瘀互结则致气血上逆,发为中风。谢老认为“肝肾亏虚”是中风的核心病机,病位在脑,根于肝肾,为本虚标实之证;瘀血是中风发病过程中的诱发或致病因素;痰湿贯穿于中风的发病过程,痰阻脑络证是临床上最常见的中风证型。针对“虚”“痰”“瘀”的病机,创立了预防中风的基础方丹桔合剂,可以滋补肝肾、化痰祛浊、活血化瘀,还可以抑制炎症、改善血脑屏障、减少氧化应激和细胞凋亡等而保护脑细胞。

Stroke is now one of the most common cerebrovascular diseases in middle-aged and elderly people,and its prevention is very important.Xie Changren is a national famous TCM master.Master Xie extensively collects prescriptions,inherits the essence of the ancient,and innovates new ideas.He advocates that the type of syndrome should be simple and not be complex,the prescriptions should be used and modified flexibly.Clinical prevention and treatment of cerebrovascular disease is remarkable.He stresses the importance of preventing stroke clinically.Most of the stroke diseases are deficiency of the root and excess of the branch.Liver and kidney deficiency is the foundation.The vital qi in lower-energizer is deficient and inner wind produces.The disturbance of wind and fire,coupled with exuberant phlegmdampness and blocked blood stasis,so phlegm and blood stasis leads to the ascending of qi and blood,which is stroke.Master Xie believes that deficiency of liver and kidney is the core pathogenesis of stroke,and the disease is located in the brain and rooted in the liver and kidney.It is the type of deficiency of the root and excess of the branch.Blood stasis is a predisposing or pathogenic factor in the pathogenesis of stroke.Phlegm dampness runs through the pathogenesis of stroke,and phlegm blocking cerebral collateral type is the most common clinical stroke syndrome.In view of the pathogenesis of deficiency,phlegm and blood stasis,he creates the basic formula of foundation of Danju Mixture to prevent stroke.It can nourish liver and kidney,remove phlegm and turbidity,activate blood and remove blood stasis,inhibit inflammation,improve blood-brain barrier,reduce oxidative stress and apoptosis,and protect brain cells.