吸入麻醉在儿童电子鼻咽喉镜检查中的应用效果及安全性评价

Application effect and safety evaluation of inhalation anesthesia in children’s electronic rhinopharyngeal endoscopy

目的 比较七氟醚吸入麻醉和表面局部麻醉在电子鼻咽喉镜检查过程中的应用效果。方法 选择行电子鼻咽喉镜检查的1 006例患儿作为研究对象。在遵循个人意愿的基础上使用随机数字表法将患儿分为吸入麻醉组和局部麻醉组,每组503例。比较两组患儿内镜检查的FLACC疼痛评分、黏膜损伤发生率、不良反应发生率、医生操作感受评分、完成检查所需时间及二次进镜率。结果 吸入麻醉组患儿行电子鼻咽喉镜检查其疼痛感受、黏膜损伤发生率低于局部麻醉组(P=0.002,P<0.001),且两组均未发生严重不良反应。吸入麻醉组医生操作感受及检查时间也优于局部麻醉组(P=0.042,P=0.026)。结论 在儿童电子鼻咽喉镜检查过程中,吸入麻醉优于局部麻醉效果。

Objective This study aimed to compare the application effects of sevoflurane inhalation anesthesia and topical local anesthesia in electronic rhinopharyngeal endoscopy. Methods A total of 1 006 children who underwent electronic rhinopharyngeal endoscopy were selected. The participants were divided into two groups depending on the type of anesthesia(inhalational vs. local) they received. Next, a random number table was created, with 503 participants added in each group. The FLACC pain score, the incidence of mucosal injury, the incidence of adverse reactions, the doctor’s experience score, the time needed to complete the examination and the rate of second entry were compared between the two groups. Results The incidence of pain and iatrogenic injury among the children in the inhalation anesthesia group was significantly lower than that in the local anesthesia group(P=0.002,P<0.001). No severe adverse reactions were noted in both groups. Additionally, the doctor’s experience and examination time in the inhalation anesthesia group were significantly better than those in the local anesthesia group(P=0.042,P=0.026). Conclusion For children undergoing electronic rhinopharyngeal endoscopy, inhalation anesthesia is more beneficial than local anesthesia.