气道内金属支架取出术方法学及其影响因素分析

The methodology of tracheobronchial metallic stents removal and influential factors analysis

目的 通过统计学处理分析影响气道内金属支架取出术方法学的影响因素,探讨气道内金属支架取出术的方法学。方法 收集64例气道内金属支架取出术的病历资料,进行病例对照研究。所有患者按照支架取出使用的方法种类数量,分为支架取出方法种类≤3种组(n=40)和支架取出方法种类>3种组(n=24)。比较两组患者的人口学特征、气道内金属支架类型、气道内支架留置时间、支架相关并发症等影响因素。结果 64例中有40例使用支架取出方法种类≤3种,24例使用支架取出方法种类>3种。两组患者的性别、年龄、置入支架时病因、支架留置体内时间、取出支架时支架结构完整性的差异无统计学意义。取出支架方法种类>3种组的支架覆膜情况、支架移位、支架相关肉芽组织或肿瘤组织形成程度评分、支架相关瘢痕组织形成程度评分,与取出支架方法种类≤3种组相比差异具有统计学意义。多因素分析发现,支架相关瘢痕组织形成程度评分(OR=1.354,95%CI:1.100~1.667,P=0.004)是影响气道内金属支架取出术方法学种类数量的影响因素。结论 通过研究发现气道内金属支架相关瘢痕组织形成程度是支架取出方法学种类数量的影响因素,且影响关系为正相关。

Objective The study aimed to investigate the methodology of tracheobronchial metallic stent removal and to analyze the influencing factors by statistical methods. Methods A total of 64 patients, who underwent tracheobronchial metallic stent removal, were included in this case-control study. The patients were divided into two groups: ≤3 types of stent removal methods(n=40) and >3 types of stent removal methods(n=24). The study aimed to compare the demographic characteristics, type of tracheobronchial metallic stents, duration of stent retention, stent-related complications, and other relevant factors between the two groups. Results There were 40 patients, who underwent at most three types of stent removal methods. Meanwhile, there were 24 patients, who underwent more than three types of stent removal methods. No significant statistical differences were observed between the two groups in terms of gender, age, etiology of stent implantation, duration of stent retention, and structural integrity of the stent. There were statistically significant differences between the two groups in terms of the coverage of the stent, stent migration, the stent-related granulation tissue or tumor tissue formation score, and the stent-related cicatricial tissue score. Based on the multivariate analysis, the stent-related cicatricial tissue score(OR=1.354, 95%CI:1.100-1.667, P=0.004) significantly influenced the number of tracheobronchial metallic stent removal methods. Conclusion In this study, the stent-related cicatricial tissue score significantly influenced the number of tracheobronchial metallic stent removal methods, and is the positive correlation relationship.