基于CiteSpace的人乳头瘤病毒疫苗可视化分析

Visual Analysis of Human Papillomavirus Vaccine Based on CiteSpace

目的探讨国内人乳头瘤病毒(HPV)疫苗相关领域的研究热点及发展态势,为日后的HPV疫苗的相关研究提供思路。方法收集中国知网学术期刊数据库中2011年1月-2021年12月HPV疫苗相关文献,经NoteExpress去重后共纳入1453篇文献,再利用CiteSpace对发文量、作者、机构和关键词等信息进行可视化分析。结果近10年间HPV疫苗发文量呈现上升趋势。核心作者群主要是以乔友林、魏丽惠、夏宁邵、李少伟、庄昉成等为代表的核心团队。中国医学科学院肿瘤医院、厦门大学、北京大学人民医院、中国食品药品检定研究所、中国疾病预防控制中心病毒病预防控制所等单位为主要进行相关研究的机构。关键词频次、突现和时区图显示,近年来研究的热点主要集中在HPV疫苗的对宫颈肿瘤的预防控制、研发、疫苗的接种人群、和疫苗的接受度等领域。结论利用可视化图谱分析有利于更好了解我国HPV疫苗研究现状和热点,为该领域未来的研究提供方向和思路,并为今后的发展提供借鉴和参考。

Objective To explore the research hotspots and development trends of human papillomavirus(HPV)vaccine in China,and to provide ideas for future research on HPV vaccine.Methods The literature related to HPV vaccine from January 2011 to December 2021 in the CNKI academic journal database was collected.A total of 1453 articles were included after NoteExpress deduplication.CiteSpace was used to visualize the number of articles,authors,institutions and keywords.Results The number of HPV vaccine publications showed an upward trend in the past 10 years.The core author group was mainly the core team represented by QIAO You-lin,WEI Li-hui,XIA Ning-shao,LI Shao-wei and ZHUANG Fang-cheng.Cancer Hospital Chinese Academy of Medical Sciences,Xiamen University,Peking University People’s Hospital,National Institute for Food and Drug Control,National Institute of Viral Disease Control and Prevention,Chinese Center for Disease Control and Prevention were the main research institutions.The graphs of frequency,occurrence and time zone showed that the research hotspots in recent years mainly focus on HPV vaccine for cervical cancer prevention and control,research and development,vaccine vaccination population,and vaccine acceptance.Conclusion Visualization analysis is helpful to better understand the current situation and hot spots of HPV vaccine research in China,provide direction and ideas for future research in this field,and provide reference for future development.