抗菌药物对肿瘤治疗的影响

Effect of antibacterials on tumor therapy

恶性肿瘤患者是感染的高危人群,抗菌药物是防治感染的重要手段。抗菌药物可通过作用于人体肠道微生物生态系统,对肿瘤治疗产生影响。近年来,肠道菌群与肿瘤的相关性成为人们关注的焦点,研究表明肠道微生物与肿瘤治疗疗效和药物不良反应密切相关。该文综述了抗菌药物对恶性肿瘤的免疫治疗、化疗和放疗的影响,以期为临床的肿瘤治疗提供新思路。

Patients with malignant tumors are at high risk for infection, and antibacterials are crucial means of infection control and prevention. Antibacterials can influence tumor therapy by acting on human intestinal microbial ecosystem.In recent years, correlation between gut microbiota and tumors has become focus of attention. Studies have shown that gut microbiota are closely related to tumor therapy and adverse drug reactions. With the goal of providing insights into clinical tumor therapy and new ideas, this review article describes the effects of antibacterials on tumor immunotherapy,chemotherapy and radiotherapy.