沙特阿拉伯某中国企业2020年367例中国籍新型冠状病毒肺炎病例中医临床特征分析

Analysis of TCM clinical characteristics of 367 Chinese COVID-19 cases in a Chinese enterprise in Saudi Arabia in 2020

目的分析沙特阿拉伯367例中国籍新型冠状病毒肺炎患者临床资料及中医证候,为该病的中医防治提供科学依据。方法将在沙特阿拉伯吉赞地区某中国企业2020年5月期间诊断为新型冠状病毒肺炎的患者纳为研究对象,收集患者基本情况、中医症状、舌象、脉象,数据用频数(n)和百分率表示。中医证候采用频数统计和聚类分析,并结合临床进行辨证。结果收集的367例新型冠状病毒肺炎患者平均年龄为(40.52±8.54)岁,均为男性,有基础病者6例;其中症状为胸闷者183例(49.86%)、咳嗽161例(43.87%)、乏力142例(38.69%)、肌肉酸痛136例(37.06%)、食欲下降123例(33.51%)、腹泻119(32.43%)、咽痛119例(32.43%)、口干116例(31.61%)、口苦94例(25.61%)、焦虑83例(22.62%)等;舌象以红舌(223例,60.76%)、腻苔(247例,67.30%)、胖舌(42例,11.44%)多见;脉象以滑脉(215例,58.58%)、细脉(178例,48.50%)和数脉(153例,41.69%)为主;中医证型主要以湿毒郁肺证(178例,48.50%)和湿热蕴肺证(120例,32.70%)为常见。结论本研究纳入的沙特阿拉伯中国籍新型冠状病毒肺炎患者的中医证候以湿毒郁肺证与湿热蕴肺证为主。湿、热、毒为核心病机,根据此特点,可针对性地采取中医药治疗。

Objective To analyze the clinical data and TCM evidence of 367 patients with COVID-19 in Saudi Arabia and provide a scientific basis for the prevention and treatment of this disease in TCM.Methods Patients diagnosed with COVID-19 during May 2020 in a Chinese enterprise in Jizan region of Saudi Arabia were included in the study,and their basic conditions,TCM symptoms,tongue signs and pulse signs were collected.The data are expressed in frequency(n)and percentage(%).Traditional Chinese medicine syndrome uses frequency statistics and cluster analysis,combined with clinical syndrome differentiation.Results The mean age of patients with COVID-19 was(40.52±8.54)years old,all were male,and 6 participants had concomitant diseases;symptoms included chest tightness in 183 cases(49.86%),cough in 161 cases(43.87%),weakness in 142 cases(38.69%),muscle aches in 136 cases(37.06%),decreased appetite in 123 cases(33.51%),diarrhea in 119 cases(32.43%),and sore throat in 119 cases(32.43%),dry mouth in 116 cases(31.61%),bitter mouth in 94 cases(25.61%),and anxiety in 83 cases(22.62%);red tongue(223 cases,60.76%),greasy fur(247 cases,67.30%),and fat tongue(42 cases,11.44%)were more common;the dominant pulses were Smooth pulse(215 cases,58.58%),thready pulse(178 cases,48.50%),and rapid pulse(153 cases,41.69%).The main types of TCM symptoms were toxic stagnation of lung(178 cases,48.50%)and damp-heat accumulating in lung(120 cases,32.70%).Conclusion In this study,we found that the TCM symptoms of Chinese patients in Saudi Arabia with COVID-19 were dominated by the toxic stagnation of lung and damp-heat accumulating in lung.Dampness,heat and toxicity are the core pathogenic mechanisms,and according to this feature,Chinese medicine treatment can be targeted in a appropriate way.