腹腔镜下右半结肠根治性切除术对结肠癌患者胃肠功能、复发转移及生存情况的影响

Effect of laparoscopic radical right hemicolectomy on gastrointestinal function,recurrence, metastasis, and survival in patients with colon cancer

目的 探讨腹腔镜下右半结肠根治性切除术对结肠癌患者胃肠功能、复发转移及生存情况的影响。方法 根据手术方式的不同将107例右半结肠癌患者分为研究组(n=55)和对照组(n=52),研究组患者接受腹腔镜下右半结肠根治性切除术,对照组患者接受常规开腹手术。比较两组患者的手术相关指标、胃肠功能恢复指标、复发转移情况、生存情况及并发症发生情况。结果 研究组患者的手术时间明显长于对照组,术中出血量明显少于对照组,住院时间明显短于对照组,差异均有统计学意义(P﹤0.01)。研究组患者肠鸣音恢复时间、首次排气时间、恢复进食时间均明显短于对照组,差异均有统计学意义(P﹤0.01)。两组患者1、3、5年复发转移率及生存率比较,差异均无统计学意义(P﹥0.05)。研究组患者的并发症总发生率低于对照组(P﹤0.05)。结论 腹腔镜下右半结肠根治性切除术治疗结肠癌疗效显著,能够有效促进患者胃肠功能恢复,且安全性较高,值得临床推广应用。

Objective To investigate the effect of laparoscopic radical right hemicolectomy on gastrointestinal function, recurrence, metastasis, and survival in patients with colon cancer. Method A total of 107 patients with right hemicolon cancer were divided into the study group(n=55) and the control group(n=52) according to different surgical methods.Patients in the study group received laparoscopic radical right hemicolectomy, and patients in the control group received conventional laparotomy. The surgery-related indicators, gastrointestinal function recovery indicators, recurrence and metastasis, survival, and complications were compared between the two groups. Result The operation time in the study group was significantly longer than that of the control group, the intraoperative blood loss volume was significantly less than that in the control group, and the hospital stay was significantly shorter than that in the control group, the differences were statistically significant(P<0.01). The bowel sound recovery time, first exhaust time, and resumption time in the study group were significantly shorter than those in the control group, and the differences were statistically significant(P<0.01). There were no significant differences in the 1-, 3-, and 5-year recurrence and metastasis rates and overall survival rate between the two groups(P>0.05). The total incidence of complications in the study group was lower than that in the control group(P<0.05). Conclusion It is effective to employ laparoscopic radical right hemicolectomy in the treatment of colon cancer, which could promote the recovery of gastrointestinal function with high safety, and would be widely used in clinical practice.