雀舌黄杨中生物碱成分的研究

Study on the Alkaloids from Buxus bodinieri

用甲醇溶剂对黄杨科黄杨属雀舌黄杨(Buxus bodinieri)的地上部分进行回流提取,采用硅胶、氧化铝、葡聚糖凝胶和半制备HPLC对提取物进行分离纯化,根据理化性质及波谱数据以及与文献数据的比对,从中分离鉴定了10个生物碱化合物,分别为cyclobuxoviridine(1)、N-dimethylcycloxobuxovircine(2)、cyclovirobuxine C(3)、cyclovirobuxine A(4)、cycloprotobuxine C(5)、cycloprotobuxine A(6)、cyclobuxoxazine(7)、cyclobuxoxazine A(8)、buxruguline B(9)和irehine(10).化合物1~9为三萜生物碱,化合物10为甾体生物碱,化合物1及3~10为首次从该植物中分离得到.

Various techniques were used to study the chemical constituents of the plant Buxus bodinieri.Ten alkaloids were isolated from their stems and leaves,which were identified as cyclobuxoviridine(1),N-dimethylcycloxobuxovircine(2),cyclovirobuxine C(3),cyclovirobuxine A(4),cycloprotobuxine C(5),cycloprotobuxine A(6),cyclobuxoxazine(7),cyclobuxoxazine A(8),buxruguline B(9),irehine(10).Compounds 1 and 3~10 were first isolated from this plant.