朝医四象体质的末梢神经活动电位特征性变化机制研究

Activity Potential Differences of Peripheral Nerve between Yin and Yang

目的:阐述朝医四象体质的末梢神经活动电位(PNAP)特征性变化机制,为朝医体质诊断与治疗提供依据。方法:以健康志愿者990名为对象进行朝医辨象,并检测正中、尺、腓和胫神经CMAP和F波,分析四象组间及组内的神经传导机能特征性变化。结果:(1)太阴和少阳人正中神经MCV右侧较左侧下降,少阳人尺、胫神经MCV左侧较右侧下降,太阴和少阴人尺、腓、胫神经MCV左侧较右侧下降(P<0.05);(2)太阴人正中、胫神经波幅(DA)、MCV,以及尺神经DA较少阳人下降(P<0.05)。太阴人正中神经DA,胫神经DA、MCV较少阴人下降(P<0.05)。少阴人正中神经MCV较少阳人下降(P<0.05);(3)正中神经AMP./DUR.比值,少阴人>少阳人>太阴人(P<0.05)。结论:正中神经以左侧为传导优势,尺、胫神经以右为传导优势,且太阴人左右差异最大。少阳人末梢神经传导机能优于太阴、少阴人,正中神经AMP./DUR.比值敏感反映体质差异。

Objective:This paper explains the characteristic changing-mechanism of peripheral nerve activity potential(PNAP) of Korean Medicine Sasang constitution to provide a basis for the diagnosis and treatment of Korean Medicine constitution.Methods:990 healthy people were identified by Korean Medicine, and CMAP and F waves of median, ulnar, peroneal and tibial nerves were detected to analyze the characteristic changes of nerve conduction function between and within Sasang groups.Results:In Taiyin, the right MCV of the median nerve decreased, and the left MCV of the ulnar, peroneal and tibial nerves decreased;in Shaoyang, the right MCV of median nerve decreased, and left MCV of ulnar and tibial nerve decreased;in Shaoyin, the left MCV of ulnar, peroneal and tibial nerves decreased(P<0.05).Taiyin compared with Shaoyang, amplitude(DA)and MCV of median and tibial nerve, and ulnar nerve DA decreased(P<0.05);Taiyin compared with Shaoyin, median nerve DA,tibial nerve DA and MCV decreased(P<0.05);Shaoyin compared with Shaoyang, median nerve MCV decreased(P<0.05).Ratio(AMP/DUR) of median nerve, Shaoyin>Shaoyang>Taiyin(P<0.05).Conclusion:The left median nerve and the right ulnar and tibial nerve have an advantage in conduction, and the largest difference between the left and the right is in Taiyin.The peripheral nerve conduction parameters of Shaoyang are better than those of Taiyin and Shaoyin, and the median nerve Ratio(AMP/DUR) sensitively reflects physical differences.