蒙医灸疗配合嘎日西辅助治疗化疗致食欲减退疗效观察

Effect of Mongolian Medicine Moxibustion Combined with Garixi on Anorexia Caused by Chemotherapy

目的:评价蒙医灸疗配合嘎日西(消食十味丸+六味安消散)辅助治疗恶性肿瘤患者化疗所致食欲减退的临床疗效。方法:将72例患者随机分为对照组(A组,n=24)、疗术组(B组,n=24)、观察组(C组,n=24)。A组自化疗第1天起,依照CINV的治疗指南给予西医常规治疗。B组自化疗第1天起,在A组的常规治疗基础上给予蒙医间接灸疗法治疗。C组自化疗第1天起,在A组的常规治疗基础上给予蒙医间接灸配合蒙药嘎日西治疗。每组疗程均为5天,观察1~5天患者食欲情况及生活质量评分,统计分析3组的指标数据。结果:食欲减退情况比较:第3天C组和A组间有显著统计学差异(P<0.01);第4天C组和A组间有显著统计学差异(P<0.01),C组和B组间有显著统计学差异(P<0.01);第5天C组和A组间有显著统计学差异(P<0.01),C组和B组间有显著统计学差异(P<0.01)。生活质量比较:治疗前后,3组组内比较,有统计学差异(P<0.05),B组和C组差异显著(P<0.01);治疗后3组间比较无统计学差异(P>0.05)。临床疗效:化疗第2天A组有效率0%,B组有效率8.33%,C组有效率4.17%;第3天A组有效率25.00%,B组有效率54.17%,C组有效率62.50%;第4天A组有效率54.17%,B组有效率54.17%,C组有效率75.00%;第5天A组有效率58.33%,B组有效率66.67%,C组有效率75.00%。结论:蒙医灸疗配合嘎日西辅助治疗可改善化疗患者的食欲,提高生活质量,有助于化学疗法的顺利进行。

Objective:To evaluate the clinical efficacy of Mongolian Moxibustion combined with Garixi(Xiaoshi Shiwei Pill+Liuwei Anxiao San) in the adjuvant treatment of anorexia caused by chemotherapy in patients with malignant tumors.Methods:72 patients were randomly divided into control group(group A,n=24),treatment group(group B,n=24) and observation group(Group C,n=24).Group A received routine treatment of Western medicine according to the treatment guidelines of CINV from the first day of chemotherapy.Group B was treated with Mongolian medicine indirect moxibustion on the basis of routine treatment in group A from the first day of chemotherapy.Group C was treated with Mongolian medicine indirect moxibustion combined with Mongolian medicine Garixi on the basis of routine treatment in group A from the first day of chemotherapy.The course of treatment was 5 days.The patients’ appetite and quality of life scores were observed for 1~5 days, and the data of the three groups were compared and analyzed.Results:Comparison of anorexia: there was significant difference between group C and group A on the third day(P<0.01);On the fourth day, there was significant difference between group C and group A(P<0.01),and there was significant difference between group C and group B(P<0.01);On the fifth day, there was significant difference between group C and group A(P<0.01),and there was significant difference between group C and group B(P<0.01);Comparison of quality of life: there was significant difference among the three groups before and after treatment(P<0.05),and there was significant difference between group B and group C(P<0.01);There was no significant difference among the three groups after treatment(P>0.05);3.Clinical efficacy: on the second day of chemotherapy, the effective rate of group A was 0%,that of group B was 8.33%,and that of group C was 4.17%.On the third day, the effective rate was 25.00% in group A,54.17% in group B and 62.50% in group C.On the fourth day, the effective rate was 54.17% in group A,54.17% in group B and 75.00% in group C.On the fifth day, the effective rate was 58.33% in group A,66.67% in group B and 75.00% in group C.Conclusion:Mongolian Moxibustion combined with Garixi adjuvant therapy can improve the appetite of chemotherapy patients, and its curative effect is equivalent.Improving the quality of life is conducive to the smooth progress of chemotherapy.