摘要壶腹部腺癌是起源于Vater壶腹(ampulla of Vater)区域的恶性肿瘤,其中Vater壶腹是指十二指肠、胰管和胆总管的交叉部位[1],其周围有肝胰壶腹括约肌以及胆总管和胰管末段的括约肌包绕。肝脏分泌的胆汁以及胰腺分泌的胰液经过此区域进入十二指肠,协助机体消化食物。发生于此部位的肿瘤,早期无明显临床症状。随着肿瘤进展,其压迫周围重要脏器,可出现急性胰腺炎,黄疸等症状。
3Howlader N,Noone AM,Krapcho M,et al. SEER Cancer StatisticsReview, 1975-2010, National Cancer Institute. Bethesda, MD.http://seer.cancer.gov/csr/1975_2010/results_merged/sect_22_pancreas.pdf. Accessed May 17,2013.
4Lynn M. Matrisian,Rhonda Aizenberg, Aliison Rosenzweig. Thealarming rise of pancreatic cancer deaths in the United StatesiWhywe need to stem the tide today, http://www.pancan.org/section_research/reports/pd?/incidence_report_2012.pdf. PublishedAugust 2012. Accessed May 17,2013.
5Conlon KC,Klimstra DS,Brennan MF. Long-term survival aftercurative r^sectionfor pancreatic ductal adenocarcinoma: clinico-pathologicanalysis of 5-year survivors. Ann Surg, 1996,223:273-279.
6Varadhachary GR,Tamm EP,Abbruzzese JL,et al. Borderlineresectable pancreatic cancer: definitions, management, and role ofpreoperative therapy. Ann Surg Oncol, 2006,13:1035-1046.
7Bilimoria KY,Talamonti MS, Sener SF,et al. Effect of hospitalvolume on margin status after pancreaticoduodenectomy forcancer. J Am Coll Surg, 2008,7:510-519.
8Hernandez J, Mullinax J, Clark W, et al.Survival after pancrea-ticoduodenectomy is not improved by extending resections toachieve negative margins. Ann Surg, 2009,50:76-80.
9Tamm EP, Balachandran A, Bhosale PR,et al. Imaging ofpancreatic adenocarcinoma : update on staging/resectability.Radiol Clin North Am, 2012,50:407-428.
10Edge SB,Compton CC. The American Joint Committee on Cancer:the 7th edition of the AJCC cancer staging manual and the futureofTNM. Ann Surg Oncol, 2010,17:1471-1474.
2Wenming Wu,Jie Chen,Chunmei Bai,Yihebali Chi,Yiqi Du,Shiting Feng,Li Huo,Yuxin Jiang,Jingnan Li,Wenhui Lou,Jie Luo,Chenghao Shao,Lin Shen,Feng Wang,Liwei Wang,Ou Wang,Yu Wang,Huanwen Wu,Xiaoping Xing,Jianming Xu,Huadan Xue,Ling Xue,Yang Yang,Xianjun Yu,Chunhui Yuan,Hong Zhao,Xiongzeng Zhu,Yupei Zhao,on behalf of the Chinese Pancreatic Surgery Association.The Chinese guidelines for the diagnosis and treatment of pancreatic neuroendocrine neoplasms(2020)[J].Journal of Pancreatology,2021,4(1):1-17. 被引量:2