Extending genetic risk for Alzheimer's disease from host to holobiont

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摘要 The gut microbiota is implicated in risk for Alzheimer's disease (AD). A study in Science reports that depleting gut bacteriain mice with genetic risk for AD reduces neuropathology in a sex-dependent manner. This is reversed by administering short-chainfatty acids, suggesting that specific bacterial metabolites increase susceptibility to AD.

作者 Sabeen A Kazmi

机构地区不详

出处《四川生理科学杂志》 2023年第2期283-283,共1页 Sichuan Journal of Physiological Sciences

关键词 ALZHEIMER PATHOLOGY reversed

分类号 R74 [医药卫生—神经病学与精神病学]

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四川生理科学杂志

2023年第2期

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Extending genetic risk for Alzheimer's disease from host to holobiont

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