奥迪括约肌功能与胆道系统疾病的临床争议

Clinical disputes between sphincter of Oddi function and biliary system diseases

奥迪括约肌的功能与胆道系统(包括胆囊和胆管)疾病的关系非常复杂。内镜切开奥迪括约肌取出胆总管结石后,是否需要常规加行腹腔镜胆囊切除术,目前国际上尚有争议。这是一个常见且重要需要解答的临床问题。笔者广泛而深入地阅读相关文献,总结并分析相关研究成果,基于科学性层面,从奥迪括约肌的解剖和功能、奥迪括约肌功能障碍或不协调导致的胆道疾病、奥迪括约肌受人工破坏后对患者胆囊和胆管的影响等方面回答该临床问题。

The link between sphincter of Oddi function with biliary system(gallbladder and bile duct)diseases is considered to be very complicated.Whether routine prophylactic laparos-copic cholecystectomy should be carried out after endoscopic sphincterotomy to remove bile duct stones has been controversial worldwide.Actually,this is a very common and important clinical question which needs to be answered.The author spends a lot of time and efforts to broadly read and analyze on published articles related to this topic,and tries,from the aspects of the anatomy and function of sphincter of Oddi,the biliary diseases causing by dysfunction or discordance of sphincter of Oddi,and the impacting of artificial destruction of sphincter of Oddi on the gallbladder and bile duct of patients,to come up with an answer to this question based on scientific and medical evidence.