影像学检查在多系统受累的朗格汉斯细胞组织细胞增生症诊断中的应用价值及影像学特征

Application value and imaging features of imaging examination in diagnosis of Langerhans cell histiocytosis with multi-system involvement

目的:探讨影像学检查在多系统受累的朗格汉斯细胞组织细胞增生症(MS-LCH)诊断中的应用价值及影像学特征。方法:回顾性分析2018年1月至2021年12月该院收治的50例MS-LCH患者的临床资料,观察X线、超声、CT、MRI检查在MS-LCH诊断中的价值。结果:50例MS-LCH患者中骨骼系统受累24例,肺脏受累10例,肝脏受累4例,垂体-下丘脑轴受累12例,甲状腺受累6例;其中骨骼系统受累MRI检出率为100.00%,CT检出率为83.33%,X线检出率为33.33%,差异有统计学意义(P<0.05);肝脏、肺脏受累MRI检出率为100.00%,CT检出率为85.71%,差异无统计学意义(P>0.05);垂体-下丘脑轴受累MRI检出率为100.00%;甲状腺受累CT检出率为66.67%,超声检出率为100.00%;且检查方法不同影像学特征各异。结论:影像学检查在MS-LCH诊断中具有较高的应用价值,检查方法不同影像学特征各异。

Objective:To observe application value and imaging features of imaging examination in diagnosis of Langerhans cell histiocytosis(MS-LCH)with multi-system involvement.Methods:The clinical data of 50 patients with MS-LCH admitted to the hospital from January 2018 to December 2021 were retrospectively analyzed.The value of X-ray,ultrasound,CT and MRI in the diagnosis of MS-LCH was observed.Results:Among the 50 MS-LCH patients,24 had skeletal system involvement,10 had lung involvement,4 had liver involvement,12 had hypothalamic-pituitary axis involvement,and 6 had thyroid involvement.The detection rates of MRI,CT and X-ray in skeletal system involvement were 100.00%,83.33%and 33.33%,separately,and the differences were statistically significant(P<0.05).The MRI detection rate of liver and lung involvement was 100.00%,that of CT was 85.71%,and the difference was not statistically significant(P>0.0).The MRI detection rate of hypothalamic-pituitary axis involvement was 100.00%.The detection rate of thyroid involvement was 66.67%by CT and 100.00%by ultrasound.According to different examination methods,the imaging features were different.Conclusions:Imaging examination has high application value in the diagnosis of MS-LCH,and the imaging features are different according to different examination methods.