急性心肌梗死患者左心室射血分数降低的影响因素分析

Influencing factors of decreased left ventricular ejection fraction in patients with acute myocardial infarction

目的 分析急性心肌梗死(AMI)后左心室射血分数降低的独立影响因素。方法 收集503例急性心梗患者临床资料,用Lasso回归及多因素logistic回归分析左心室射血分数降低的独立影响因素。结果 3支冠脉病变、感染、NT-proBNP超过参考值的10倍和住院期间进行非急诊PCI术治疗是AMI患者射血分数降低的独立影响因素。结论 3支冠脉病变、感染、NT-proBNP超过参考值的10倍为独立危险因素,住院期间非急诊PCI治疗恢复冠脉血运供应为独立保护因素。

Objective To analyze the independent influencing factors of decreased left ventricular ejection fraction(LVEF) after acute myocardial infarction(AMI). Methods Clinical data of 503 AMI cases were collected. The independent influencing factors of decreased LVEF were analyzed by Lasso regression and multivariate logistic regression. Results Three coronary involvement, infection, NT-proBNP level > upper reference limit by 10 times, and non-emergency PCI during hospitalization were independent influencing factors for decreased LVEF. Conclusion Three coronary involvement, infection,and NT-proBNP level > upper reference limit by 10 times are independent risk factors, while coronary blood restoration of nonemergency PCI during hospitalization is an independent protective factor.