子宫内膜疾病对女性生育健康影响的研究进展

Research update on the impact of endometrial diseases on women's reproductive health

子宫内膜在胚胎着床过程发挥着至关重要的作用,内膜异常可直接导致不孕。除机械性因素外,子宫内膜良性和恶性疾病导致生育力下降的具体机制尚不详,治疗方式与助孕时机也存在争议。本文从常见的子宫内膜良性和恶性疾病的临床流行病学特点、与不孕的相关性及其病理生理机制、主要干预措施及效果等方面追踪了国内外基础与临床研究进展,系统分析了其对女性生育力的影响,为有效地制定临床治疗策略、进一步提高临床疗效提供借鉴和参考。

The endometrium plays a crucial role in the process of embryo implantation,and abnormalities of the endometrium can directly lead to infertility.In addition to mechanical factors,the specific mechanism of impaired fertility caused by benign and malignant endometrial diseases is still unknown.Also,the treatment and appropriate timing of assisted reproduction are controversial.This review tracked recent basic and clinical researches both national and international,and made a summarize from the point of view of epidemiological characteristics,correlation with infertility,pathophysiological mechanisms,main interventions of common benign and malignant endometrial diseases.The main goal is to systematically evaluate the impact of endometrial diseases on female fertility,and provides a reference for clinical intervention strategies to improve clinical efficacy further.