纤维-骨肿瘤及结构不良的临床病理特征与鉴别诊断

Clinical and pathological features and differential diagnosis of fibro-osseous tumors and dysplasias

纤维-骨病变是在临床表现和病理学特征上有明显相似性的一类疾病, 一直受到临床医师以及病理医师的关注。2022年WHO第5版头颈部肿瘤的最新分类将其中牙骨质-骨结构不良、节段性牙上颌结构不良、纤维结构不良、青少年小梁状骨化纤维瘤、沙瘤样骨化纤维瘤和家族性巨大型牙骨质瘤等6种疾病列入"纤维-骨肿瘤及结构不良", 并对这些疾病的诊断和治疗提出了新的观点。本文根据2022年WHO最新分类, 对这6种疾病的临床病理特征、诊断和鉴别诊断进行阐述, 以期为临床诊疗提供参考。

Fibro-osseous lesions is a class of diseases with obvious similarities in clinical manifestations and pathological features,which has been attracting the attention of clinicians and pathologists.The latest WHO 2022 Classification(5th edition)included six of these diseases(cemento-osseous dysplasia,segmental odontomaxillary dysplasia,fibrous dysplasia,juvenile trabecular ossifying fibroma,psammomatoid ossifying fibroma and familial gigantiform cementoma)in the"fibro-osseous tumours and dysplasias",and put forward new ideas on the diagnosis and treatment of these diseases.According to the latest WHO 2022 Classification(5th edition),the clinical and pathological features,diagnosis and differential diagnosis of these six diseases were described.