中西医结合治疗对晚期卵巢癌患者免疫学指标的影响

Influence of integrated traditional Chinese and western medicine on immunological indexes in patients with advanced ovarian cancer

目的探究中西医结合治疗对晚期卵巢癌患者免疫学指标的影响。方法将2018年2月—2020年2月收治的60例晚期卵巢癌患者作为研究对象,按时间先后分为2组,各30例。对照组采用化疗,观察组采用化疗+中药方剂治疗,比较2组治疗效果。结果对照组有效率40.0%,低于观察组的63.33%,差异有统计学意义(P<0.05)。治疗前,2组免疫功能情况无统计学差异(P>0.05);经过治疗,观察组CD_(3)^(+)、CD_(4)^(+)、CD_(4)^(+)/CD_(8)^(+)高于对照组,CD8+低于对照组,均有统计学差异(P<0.05)。观察组不良反应发生率低于对照组,有统计学差异(P<0.05)。结论中西医结合治疗可改善晚期卵巢癌患者免疫功能,安全性良好,值得推广。

Objective To explore the effect of integrated traditional Chinese and Western medicine treatment on immunological indicators of patients with advanced ovarian cancer.MethodsFrom February,2018 to February,2020,60 patients with advanced ovarian cancer were treated as research subjects.They were divided into groups by random number table,30 cases in each group.The control group was treated with chemotherapy,and the observation group was treated with chemotherapy+traditional Chinese medicine.Comparison of treatment effects between the two groups.Results The effective rate of 40.0%in the control group was lower than 63.33%in the observation group,which was statistically significant(P<0.05).Before treatment,there was no significant difference in immune function between the two groups(P>0.05);after treatment,CD_(3)^(+),CD_(4)^(+),CD_(4)^(+)/CD_(8)^(+) in the observation group were higher than those in the control group,and CD8^(+) in the observation group was lower than the control group.There were statistical differences in data(P<0.05).The incidence of adverse reactions in the observation group was lower than that in the control group,and the data was statistically different(P<0.05).Conclusion Integrated Chinese and Western medicine treatment can improve the immune function of patients with advanced ovarian cancer,and is safe and worthy of promotion.