经尿道等离子切除术与电切术治疗良性前列腺增生的效果对比研究

A Comparative Study on the Efficacy of Bipolar Transurethral Plasma Kinetic Prostatectomy and Electrical Resection in the Treatment of Benign Prostatic Hyperplasia

目的:探讨经尿道前列腺等离子双极电切术(TUPKP)与经尿道前列腺电切术(transurethral resection of the prostate,TURP)治疗良性前列腺增生(BPH)的疗效。方法:选取2021年1月—2022年1月麻城市人民医院就诊的230例BPH患者作为研究对象,按照不同手术方法将其分为TURP组(n=120)与TUPKP组(n=110);TURP组采用TURP治疗,TUPKP组采用TUPKP治疗。对比两组临床指标、远期疗效指标[国际前列腺症状评分(IPSS)、生活质量评分(QOL)、最大尿流量(Qmax)、残余尿量(PVR)]及两组术后并发症发生情况。结果:TUPKP组手术时间、置管时间及住院时间均短于TURP组(P<0.05),术中出血量小于TURP组(P<0.05),TUPKP组切除腺体重量大于TURP组(P<0.05)。术前,两组IPSS、Qmax、PVR及QOL比较差异均无统计学意义(P>0.05);术后3个月,两组IPSS、PVR及QOL均降低(P<0.05),且TUPKP组均低于TURP组(P<0.05),两组Qmax高于术前,且TUPKP组大于TURP组(P<0.05)。TUPKP组并发症发生率低于TURP组(P<0.05)。结论:与TURP相比,TUPKP手术创伤小,术中出血量少,可显著缩短手术时间、住院时间,且可有效改善前列腺症状,降低残余尿量,提升生活质量,术后并发症少。

Objective:To investigate the efficacy of bipolar transurethral plasma kinetic prostatectomy(TUPKP)and transurethral resection of prostate (TURP) in the treatment of benign prostatic hyperplasia (BPH). Method: A total of 230 BPH patients who were treated in Macheng People's Hospital from January 2021 to January 2022 were selected as the research objects, and they were divided into TURP group (n=120) and TUPKP group (n=110) according to different surgical methods. TURP group was treated with TURP, TUPKP group was treated with TUPKP. The clinical indicators, long-term efficacy indicators [international prostate symptom score (IPSS), quality of life (QOL), maximum urine flow (Qmax), postvoid residual volume (PVR)] and postoperative complications between the two groups were compared. Result: The operation time, catheterization time and hospital stay in the TUPKP group were shorter than those in the TURP group (P<0.05), the intraoperative blood loss was less than that in the TURP group (P<0.05), and the weight of the removed glands in the TUPKP group was greater than that in the TURP group (P<0.05). Before surgery, there were no significant differences in IPSS, Qmax, PVR and QOL between the two groups (P>0.05). Three months after the operation, IPSS, PVR and QOL in both groups were decreased (P<0.05), and the TUPKP group was lower than the TURP group (P<0.05), the Qmax in both groups was higher than that before operation, and the TUPKP group was greater than TURP group (P<0.05). The complication rate of TUPKP group was lower than that of TURP group (P<0.05). Conclusion: Compared with TURP, TUPKP has less trauma and less intraoperative blood loss, can significantly shorten the operation time and hospital stay, and can effectively improve prostate symptoms, reduce residual urine volume, improve quality of life, and reduce postoperative complications.