微量泵在血管活性药物使用中的最佳证据总结

Summary of best evidence for micropump use in vasoactive drugs

目的检索、评价国内外微量泵在血管活性药物使用中的相关证据,总结最佳证据。方法系统检索UpToDate、国际指南协作网、苏格兰院际指南网、美国国立指南库、加拿大安大略注册护士协会、美国静脉输液护理学会、美国食品药物管理局、Cochrane Library、OVID-JBI、PubMed、Embase、Web of Science、CINAHL、中国知网、万方数据库、维普网、中国生物医学文献服务系统等数据库或网站有关微量泵在血管活性药物使用中的相关证据,检索时间为从建库至2020年11月27日。采用澳大利亚JBI循证卫生保健中心真实性评价工具、证据等级系统,对证据质量及证据级别进行评价。结果共纳入30篇文献,从教育与培训、微量泵使用流程、微量泵管理这3个方面归纳、总结出28条证据。结论基于最佳证据实施微量泵输注血管活性药物的临床实践需要多学科团队合作,有必要开展相关教育与培训、制定并实施系统的微量泵管理策略,有利于持续推进微量泵在血管活性药物使用中的安全性、有效性。

Objective To retrieve and evaluate the evidence related to the use of micropumps in vasoactive drugs,and summarize the best evidence at home and abroad.Methods Evidence related to the use of micropumps in vasoactive drugs published up to November 27,2020 was systematically retrieved from databases such as UpToDate,International Guidelines Collaboration,Scottish Intercollegiate Guidelines Network,National Guidelines Repository,Ontario Registered Nurses Association,American Society for Intravenous Infusion Nursing,US Food and Drug Administration,Cochrane Library,OVID-JBI,PubMed,Embase,Web of Science,CINAHL,China National Knowledge Infrastructure(CNKI),VIP,and SinoMed.The quality and level of evidence were evaluated using the authenticity evaluation tool and evidence grading system of the Australian JBI Evidence-Based Health Care Center.Results A total of 30 literatures were included,and 28 pieces of evidence were summarized from three aspects:education and training,process of micropump use,and micropump management.Conclusions The clinical practice of micropump infusion of vasoactive drugs based on the best evidence requires the cooperation of multidisciplinary teams.It is necessary to carry out relevant education and training,formulate and implement a systematic micropump management strategy,which can continuously promote the safety and effectiveness of micropumps in vasoactive drugs.