体现辨证论治差异的不孕症知识图谱构建方法研究

Research on the Construction Method for Infertility Knowledge Graph Reflecting the Differences in Syndrome Differentiation and Treatment

不同医家在辨证论治、辨证结果及用药习惯上存在差异,目前已有的知识图谱只对辨证论治知识进行关联与表达,不能直观地体现辨证论治差异。以6位医家的不孕症知识图谱为基础,通过引入“医家”与“关联强度”两种关系属性,构建一个整合多位医家辨证论治知识并直观体现差异性的知识图谱。在PageRank算法对不孕症数据进行预处理的基础上,通过对辨证论治过程自定义逻辑规则,利用概率软逻辑推理关联强度。建立基于关系图注意力网络的知识融合模型,考虑关系对实体含义表达的影响,通过关系图注意力网络层加权传播与聚合邻居实体信息,得到更丰富的实体向量表示从而实现不孕症知识融合。实验结果表明,该模型具有较好的融合能力,在朱南孙-钱伯煊数据集上Hit@1、Hit@10、Hit@30、MeanRank均取得较好结果,分别达到45.63%、60.85%、91.55%、0.564。通过构建体现辨证论治差异的不孕症知识图谱,可以系统地建立多位医家辨证论治知识之间的关联,对中医个性化知识的传承与发展具有重要意义。

Variations can be observed between the dialectical results and medication treatment of doctors because doctors differentiate and treat syndromes differently.At present,existing knowledge graphs can only relate and express formulated dialectical knowledge but cannot intuitively reflect the differences in syndrome differentiation and treatment between doctors.In this study,a knowledge graph representing information on infertility integrating the knowledge on syndrome differentiation and treatment of six doctors is constructed by introducing relationship attributes indicating individual doctors and the strength of association between knowledge items.First,custom logic rules are defined for the process of syndrome differentiation and treatment;association strength is deduced by applying probabilistic soft logic based on the data describing pretreatment examinations for infertility using the PageRank algorithm.Second,this paper presents a knowledge fusion model based on a relational graph attention network;it is designed to consider the influence of relationships on expressions of the meaning of entities and to obtain a richer entity vector representation to fuse infertility knowledge by employing weighted propagation and aggregation of neighboring entity information through a relational graph attention network layer.The experimental results show that the proposed model exhibits good fusion ability and achieves optimal performance,reaching 45.63%,60.85%,91.55%,and 0.564 in terms of Hit@1,Hit@10,Hit@30,and MeanRank,respectively,on the Zhu Nansun-Qian Boxuan dataset.Thus,an infertility knowledge graph reflecting the differences in syndrome differentiation and treatment is constructed to systematically establish the associations between the knowledge provided by multiple doctors.The findings of this work are highly relevant for the inheritance and development of personalized knowledge in Traditional Chinese Medicine(TCM).