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西藏某小学一起流行性腮腺炎暴发疫情调查及疫苗保护效果分析

Survey of a mumps outbreak and analysis of protective effect of vaccine in a primary school in Tibet
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摘要 目的 调查分析西藏某小学一起流行性腮腺炎暴发疫情及疫苗保护效果,为类似疫情防控提供科学依据。方法开展病例个案调查,运用描述流行病学方法分析疫情流行特征、相关影响因素及疫苗保护效果。结果 共发现病例108例,全部病例均为学生,罹患率为6.55%(108/1 649)。共出现3代病例,以5年级学生为主,年龄在9~11岁之间,女生罹患率高于男生(χ^(2)=3.863,P=0.049);接种含腮腺炎成分疫苗(MuCV)是保护因素(RR=0.208,95%CI:0.049~0.843,VE=0.792),且接种1剂次疫苗的保护性低于接种2剂次疫苗(RR=4.722,95%CI:1.187~18.793,VE=-3.722)。结论 该疫情是一起因首发病例的不规范隔离管控导致的流行性腮腺炎暴发,接种MuCV是保护因素。 Objective To investigate an outbreak of mumps and analyze the protective effect of vaccine in a primary school in Tibet, so as to provide scientific basis for preventing and controlling similar epidemic of disease. Methods The case investigations was carried out, and the epidemiological methods were used to analyze the epidemiological characteristics,related influencing factors and and the pretective effect of vaccine. Results A total of 108 mumps cases were found out and all cases were students, with the incidence rate of 6.55%(108/1 649). There were 3 generations of cases, mainly in grade 5students, and all cases aged 9-11 years. The incidence rate of girl students was higher than that of boy students(χ^(2)=3.863, P=0.049). The vaccination of mumps-containing vaccine(MuCV) was protective factor(RR=0.208, 95%CI: 0.049-0.843, VE=0.792), and the protection of 1 dose vaccination was lower than that of 2 doses vaccination(RR=4.722, 95%CI: 1.187-18.793,VE=-3.722). Conclusions This mumps outbreak is caused by the first case without regular isolation and control. The vaccination of MuCV is the protective factor.
作者 杨国锋 王健 白玛赤列 张宝莹 YANG Guo-feng;WANG Jian;BAIMACHILIE;ZHANG Bao-ying(The Center for Disease Control and Prevention of Tibet Autonomous Region,Lhasa,Tibet 850000,China)
出处 《疾病预防控制通报》 2022年第6期19-21,39,共4页 Bulletin of Disease Control & Prevention(China)
关键词 流行性腮腺炎 暴发 疫苗 Mumps Outbreak Vaccine
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  • 1崔爱利.流行性腮腺炎病毒的分子流行病学研究[J].中国计划免疫,2006,12(6):521-526. 被引量:38
  • 2王爱霞.临床医护人员传染性疾病防治培训教材[M].北京:人民卫生出版社,2009:180-181.
  • 3冯子健.传染病突发事件处置[M].北京:人民卫生出版社,2013:11-15.
  • 4中华人民共和国卫生部.流行性腮腺炎诊断标准及处理原则GB17016-1997[S].北京:中国标准出版社,2004-08-01.
  • 5冯子健主译.传染病预防控制手册[M].北京:中国协和医科大学出版社,2008:381-384.
  • 6刘隽,苏琪茹,马超,等.不同免疫策略下流行性腮腺炎发病特征的初步比较分析.中国疫苗和免疫,2015,21(1):97.101.
  • 7H. Wang, Y. Hu, G. Zhang, et al. Meta-analysis of vaccine ef- fectiveness of mumps-containing vaccine under different immuniza- tion srategies in China[J]. Vaccine, 2014, 32(37) : 4806-12.
  • 8W. A. Orenstein, R. H. Bernier, T. J. Dondero, et al. Field e- valuation ft vaccine efficacy[J]. Bull World Health Organ, 1985, 63(6) : 10558.
  • 9R. M. Anderson, R. M. May. Immunization and herd immunity [J]. Lancet, 1990, 335(8690): 641-5.
  • 10W. Man, Z. Jin-Kou, W. Tao, et al. Mumps-containing vaccine effectiveness during outbreaks in two schools in Guangdong, China, 2012[J1. Western Pae Surveilt Response J, 2012, 3(4) : 29-32.

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