克罗恩病肛瘘疗效预测相关因素的研究进展

Progress of Research on Factors Related to Therapeutic Effect of Perianal Fistulizing Crohn’s Disease

克罗恩病肛瘘(pfCD)是克罗恩病最常见的肛周病变,其治疗主要为基于影像学评估的内外科联合治疗,但在临床中往往存在应答率低、复发率高等情况。因此,针对不同人群的特点进行更准确的疗效预测,从而改善pfCD患者的预后显得尤为重要。本文就pfCD疗效预测相关因素的研究进展作一综述,以期协助制定更有针对性的治疗策略。

Perianal fistulizing Crohn’s disease(pfCD)is the commonly seen perianal disease in Crohn’s disease(CD),and its main treatment is the combined use of medical and surgical therapy on basis of radiological assessment.However,low response rate and high recurrence rate are found in clinical practice.It is of great importance to predict the therapeutic efficacy accurately according to the individual characteristics of patients for improving the prognosis of pfCD.This article reviewed the progress of research on factors related to the therapeutic efficacy of pfCD for helping to develop more specifically targeted treatment strategies.