別嘌呤醇藥疹30例臨床分析

Clinical Study of 30 Patients with Drug Eruptions Caused by Allopurinol

目的總結並分析別嘌呤醇藥疹的發病及臨床特點。方法回顧性分析30例別嘌呤醇藥疹的臨床表現、實驗室檢查等特點以及預後等。結果別嘌呤醇藥疹具有以下特點:1.患者多為老年人;2.潛伏期長;3.患者多出現發熱;4.皮疹類型多樣;5.内臟損害多見。結論別嘌呤醇藥疹預後關鍵在於早期發現、早期治療,及時控制病情向重症發展。

Objective To analysis the clinical signs of drug eruption caused by allopurinol.Methods Clinical data from 30 cases of drug eruption caused by allopurinol were analyzed according to clinical findings,laboratory results and prognosis.Results Eruptions cause by allopurinol were characterized by①old age people②long incubation period③fever often④various patterns of skin eruptions⑤internal organ involvement.Conclusion Early diagnosis and treatment with corticosteroid are emphasized.