感染性休克早期目標導向治療效果及臨床依從性分析

Analysis of the effect and clinical compliance of early goal-directed therapy in patients with septic shock

目的對感染性休克患者早期目標導向治療(early goal-directed therapy,EGDT)的效果及臨床依從性進行回顧性分析。方法對2009年1月~2011年4月間收入鏡湖醫院ICU的54例感染性休克病例實施EGDT,統計病死率,致病原和執行EGDT各項指標的依從性,並分析相關影響因素。結果54例感染性休克患者實施EGDT後的病死率為25.9%,EGDT各項檢測指標中除SvO2外臨床依從性均達到100%,SvO2動態監測完成率只有22.2%。結論感染性休克病例實施EGDT後的病死率低於國際相關水平,提高指南的臨床依從性對最終改善感染性休克的預後有重要意義。

Objective To review and analyze the effect and clinical compliance of early goal-directed therapy(EGDT)in patients with septic shock.Methods 54 cases of patients with septic shock were admitted in ICU of Kiang Wu hospital during January 2009 to April 2011,and received treatment of early goal-directed therapy(EGDT).Statistics of the mortality,category of pathogenic organism and clinical compliance of the indicator of EGDT were carried out.Results The mortality of 54 cases with septic shock was 25.9%after receiving treatment of EGDT.Clinical compliance of the indicators of EGDT was 100%except SvO 2,while completion of dynamic monitoring of SvO 2 was only 22.2%.Conclusion After receiving treatment of early goal-directed therapy(EGDT),the mortality of the cases with septic shock is lower than that on international level.Increasing the clinical compli-ance of guideline is significant to improve the prognosis of patient with septic shock.