茶树油治疗蠕形螨性眼病的研究进展

Research progress of tea tree oil in the treatment of eye diseases caused by Demodex

眼部蠕形螨感染可造成患者眼表不适,引起多种眼部疾病,近年来发病率呈上升趋势。茶树油及其衍生物不仅有显著的杀螨效果,还具有抗菌、抗炎活性,是治疗蠕形螨性眼病的常用制剂。目前茶树油相关制剂品种多样,其安全性和最佳使用方法等均未有充分的研究证明。本文对茶树油治疗蠕形螨性眼病的机制、使用方法、安全性和疗效等方面进行综述,以期为临床治疗蠕形螨性眼病提供参考。

Ocular Demodex infection can cause discomfort of the ocular surface and a variety of ocular conditions, and the incidence has been increasing in recent years. Tea tree oil and its derivatives not only have significant acaricidal effect, but also have antibacterial and anti-inflammatory activities, and are commonly used in the treatment of Demodex eye disease. Currently, various kinds of preparations from tea tree oil are available, yet the safety and optimal use of the related extract have not been fully clarified. This paper reviewed the mechanism, application, safety and efficacy of tea tree oil in the treatment of Demodex eye conditions, with an attempt to provide reference for clinical use of this extract for ocular Demodex infestation.