摘要
系统性轻链型(AL)淀粉样变性(amyloidosis)合并多发性骨髓瘤(multiple myeloma,MM)是一种临床上罕见的浆细胞相关恶性疾病。大多数患者因心脏、肾脏功能损伤或实质性骨髓瘤为主诉就诊,以吞咽困难或其他口腔相关疾病为首发症状的病例罕见,故初诊时易漏诊误诊。本文报告1例以吞咽困难为首发症状的淀粉样变性合并多发性骨髓瘤病例,结合相关文献,对该病的特点、诊断标准及治疗方法进行讨论。
Systemic light-chain-type amyloidosis combined with multiple myeloma(MM) is a clinically rare plasma cellassociated malignant disease.Most of the patients with this disease are complained for heart/renal impairment or substan-tial myeloma,and very few cases presented dysphagia or other oral related diseases as the first symptom,so it is easy to miss diagnosis or make misdiagnosis during first visit.Therefore,the diagnosis and treatment of amyloidosis with dysphagia was reported in the article.Based on the relevant literature review,the characteristics,diagnostic criteria and treatment of the disease were discussed.
作者
陈霖
陈寅瑜
丁紫雪
孟箭
CHEN Lin;CHEN Yin-yu;DING Zi-xue;MENG Jian(Xuzhou Clinical College of Xuzhou Medical University,Xuzhou 221000;Department of Stomatology,Xuzhou Central Hospital,Xuzhou 221000;School of Stomatology,Xuzhou Medical University,Xuzhou 221000,Jiangsu Province,China)
出处
《中国口腔颌面外科杂志》
CAS
2023年第1期97-101,共5页
China Journal of Oral and Maxillofacial Surgery
基金
徐州市重点研发计划(20210230)。
关键词
淀粉样变
多发性骨髓瘤
吞咽困难
舌疾病
口腔颌面部
Amyloidosis
Multiple myeloma
Dysphagia
Diseases of tongue
Oromaxillofacial region