兩種輔助通氣在新生兒暫時性呼吸增快症並呼吸衰竭的療效分析

Comparison of clinical efficacy of two modes of assisted ventilation in transient tachypnea of the newborn

目的比較加溫濕化經鼻導管高流量通氣(HHHFNC)和鼻塞式持續氣道正壓通氣(NCPAP),應用於新生兒暫時性呼吸增快症(TTN)並呼吸衰竭的臨床療效。方法回顧分析本院收治之足月新生兒暫時性呼吸增快症並呼吸衰竭共40例,一組以HHHFNC治療,另一組以NCPAP治療,分析兩組患兒臨床症狀,血氣分析改善情況及併發症的發生率。結果與NCPAP組相比,HHHFNC組患兒開奶時間提前,腹脹發生率較低,而整體通氣時間,住院時間及通氣失敗率無差異。治療前後血氣分析方面,兩組在二氧化碳分壓改善方面無差異,在氧分壓方面以NCPAP組較優。結論與NCPAP組相比,HHHFNC有相關損傷小、耐受性更好之特點,是可以首選作為治療新生兒暫時性呼吸增快症的輔助通氣方式。

Objective To compare the clinical efficacy between Heated Humidified High Flow Nasal Cannula(HHHFNC)and Nasal Continuous Positive Airway Pressure(NCPAP)in the treatment of Transient Tachypnea of the Newborn(TTN)in term neonate.Methods A review of 40 cases of TTN who were supported with HHHFNC and NCPAP respectively,clinical symptoms were observed.Results The HHHFNC group had earlier first milk feeding,less complication of abdominal distension.No discrepancy in ventilation time,hospital stay and intubation rate.PaCO2 were well improved in both group.For PaO2,NCPAP group was noted to have a better improvement.Conclusion Compared with NCPAP,HHHFNC causes less comlication and has better tolerability,and can be considered the first choice of assisted ventilation in the treatment of TTN.