結直腸腫瘤與胃幽門螺旋桿菌感染的相關性分析

Relationship analysis between colorectal neoplasm and Helicobacter pylori infection

目的探討結直腸腫瘤與胃幽門螺旋桿菌(Helicobacter pylori,Hp)感染的相關性。方法收集同時進行腸鏡和胃鏡檢查的853例病理資料。根據腸鏡病理檢查結果,病人分為腫瘤組和非腫瘤組,比較兩組胃Hp感染率的差異,並分析結直腸腫瘤的個數和良惡性性質與胃Hp感染率的關係。結果結直腸腫瘤組胃Hp感染陽性率為24.2%,非腫瘤組為18.1%,兩組感染率的差異有統計學意義(P<0.05)。在結直腸腫瘤組中,胃Hp感染與腫瘤個數和良惡性性質無明顯相關性(P>0.05)。結論胃Hp感染增加結直腸腫瘤發生的風險。

Objective To investigate the relationship between colorectal neoplasm and gastric Helicobacter pylori(Hp)infection.Methods A total of 853 patients underwent colonoscopic and gastroscopic checks at the same time were collected.According to the colonoscopic and pathologic results,the patients were divided into colorectal neoplasm and non-colorectal neoplasm groups.The difference in Hp infection rate between both groups was compared.The relationship between the number and nature of colorectal neoplasm and Hp infection rate were analyzed.Results Positive rate of Hp infection was 24.2%in the colorectal neoplasm group and 18.1%in the non-neoplasm group,the difference of infection rate in both groups was statistically significant(P<0.05).There was no significance between colorectal neoplasm and Hp infection(P>0.05).Conclusion Hp infection can increase the risk of colorectal neoplasm.