摘要
炎症反应通常被认为是一种病理过程,机体多器官炎症性疾病的发生通常伴有炎症反应。持续存在的炎症反应最终可导致器官的功能障碍。近年来,对于间充质干细胞(MSC)来源的外泌体的研究发现了其独特的抗炎作用,为治疗多器官炎症性疾病提供了新思路。本文就MSC来源的外泌体在多器官(如脑部、心脏、肺部、肝脏、肾脏、肠道)炎症性疾病中的作用作一综述。
Inflammatory reaction is often considered a pathological process,and the occurrence of multi-organ inflammatory diseases of the body is usually accompanied by an inflammatory reaction.In recent years,the study of mesenchymal stem cell(MSC)-derived exosomes has discovered its unique anti-inflammatory effect,providing new ideas for the treatment of multi-organ inflammatory diseases.This article reviews the role of MSC-derived exosomes in inflammatory diseases of multi-organ(such as brain,heart,lung,liver,kidney and intestine).
作者
李洋洋
周彪
巴特
王宏宇
高仪轩
Li Yangyang;Zhou Biao;Ba Te;Wang Hongyu;Gao Yixuan(Third Clinical College of Inner Mongolia Medical University,Baotou 014010,China;Department of Burn,Inner Mongolia Baogang Hospital,Inner Mongolia Institute of Burn Medicine,Baotou 014010,China;Department of Burns and Plastic Surgery,Air Force Medical Center of PLA,Beijing 100142,China)
出处
《中华损伤与修复杂志（电子版）》
CAS
2023年第1期86-89,共4页
Chinese Journal of Injury Repair and Wound Healing(Electronic Edition)
基金
重大疾病防治科技行动计划(2018-ZX-01S-001)
内蒙古自治区自然科学基金项目(2020MS08002)
内蒙古自治区自然科学基金项目(2020MS08181)
内蒙古自治区科技创新引导项目(CXYD2020BT03)。
关键词
炎症
脑
心脏
肺
器官
外泌体
间充质干细胞
Inflammation
Brain
Heart
Lung
Exosomes
Mesenchymal stem cells
