摘要
目的分析视网膜母细胞瘤(RB)超声影像表现,探讨超声在RB诊断中的影像学价值。方法选取2013年9月至2020年7月在河北省眼科医院就诊的RB患者83例(83只眼)术后经病理确诊为RB患儿的眼部超声影像特征进行回顾性分析。其中男性43例(43只眼),女性40例(40只眼),年龄(2.08±1.65)岁(2个月至9岁)。结果本组病例RB的眼部超声均表现为起自后方球壁的球内实性肿物声像,其中表现为半球形12只眼,球形14只眼,不规则形17只眼,充满玻璃体腔形32只眼,延视网膜弥漫生长8只眼。方差分析结果显示肿物基底部宽度与高度:不规则形>球形>半球形,差异均具有统计学意义(F=17.189、12.460,P<0.001),LSD-t检验:半球形与球形、半球形与不规则形两两比较差异均有统计学意义(基底部高度比较t=-4.927,-3.784,P<0.05,宽度比较t=-4.436,-5.028,P<0.05),球形与不规则形两两比较高度没有统计学意义,宽度有统计学意义(基底部高度比较t=0.615,P>0.05,宽度比较t=-2.464,P<0.05)。其中77只眼出现钙斑,钙斑伴声影62只眼,未见明显声影15只眼。8只眼继发完全视网膜脱离,15只眼继发部分视网膜脱离。结论RB具有特征性超声影像,超声在RB的早期诊断、术前诊断及鉴别诊断中具有重要的价值。
Objective To analyze the ultrasonographic manifestations of retinoblastoma(RB)and to explore the imaging value of ultrasound in the diagnosis of RB.Methods In this retrospective cases series,83 cases(83 eyes)who were doagnosed with RB at the Department of Ophthalmology in Hebei Eye Hospital from September 2013 to July 2020 were selected.There were 43 males(43 eyes)and 40 females(40 eyes),with a minimum age of 2 months,a maximum age of 9 years,and an average age of 2.08±1.65 years.Results In this study,the ocular ultrasonography of RB showed solid bulbous masses from the posterior bulbous wall,including hemispherical mass in 12 cases(12 eyes),spherical mass in 14 cases(14 eyes),irregular shape in 17 cases(17 eyes),full vitreous cavity in 32 cases(32 eyes)and diffuse retina growth in 8 cases(8 eyes).The results of variance analysis showed that the width and height of the base of the mass were irregular>spherical>hemispherical,with statistically significant differences(F=17.189,12.460,P<0.001).LSD-t test:The Pairwise comparison between hemispherical and spherical shape and between hemispherical and irregular shape showed statistical significance(base height comparison t=-4.927,-3.784,P<0.05,width comparison t=-4.436,-5.028,P<0.05),while the pairwise comparison between spherical and irregular shape showed no statistical significance.The width was statistically significant(base height comparison t=0.615,P>0.05,width comparison t=-2.464,P<0.05).There were 77 cases(77 eyes)of calcium plaque,62 cases(62 eyes)of calcium plaque with acoustic shadow,and 15 cases(15 eyes)of no obvious acoustic shadow.Total retinal detachment occurred in 8 cases(8 eyes)and partial retinal detachment occurred in 15 cases(15 eyes).Conclusions RB has a characteristic ultrasonic appearance.B-mode ultrasonography is of great value in the early diagnosis,preoperative diagnosis and differential diagnosis of RB.
作者
赵云
郭金喜
许建锋
解铭
Zhao Yun;Guo Jinxi;Xu Jianfeng;Xie Ming(Hebei Ophthalmological Hopital,Hebei Prorincial Key Laboratory of Ophthalmology,Hebei Clincal Medical Research Center of Eye Diseases,Xingtai 054001,China)
出处
《临床眼科杂志》
2023年第1期53-56,共4页
Journal of Clinical Ophthalmology
基金
邢台市科技计划项目(编号:2022ZC238)。