肝功能异常患者进行自身抗体与免疫性肝病检查对疾病诊断准确率的影响

The Influence of Autoantibodies and Immunological Liver Diseases on the Accuracy of Disease Diagnosis in Patients with Abnormal Liver Function

研究了肝功能异常患者进行自身抗体与免疫性肝病检查对疾病诊断准确率的影响。以遂宁市中心医院收治的80例肝功能异常患者作为受检对象,对其实施自身抗体与免疫性肝病检查,观察其对疾病诊断准确率的影响。所有患者的ANA、SMA、LKM-1、LC-1、AMA-M2、SLA/LP阳性检测率明显上升,57例AIH患者中多种亚型检测数据为AIH-I38例,AIH-Ⅱ11例,AIH-Ⅲ8例,23例PBC患者ALT、AST水平明显上升,表明AIH患者伴程度不同的肝脏损伤,ALT、AST显著上升。研究发现,自身抗体与免疫性肝病检查能够更为准确地诊断肝功能异常,临床具有积极意义。

To study the influence of autoantibodies and immune liver diseases on the accuracy of disease diagnosis in patients with abnormal liver function.Taking 80 patients with abnormal liver function collected in Suining Central Hospital as subjects,the autoantibodies and immune liver diseases were examined to observe their influence on the accuracy of disease diagnosis.The positive detection rate of ANA,SMA,LKM-1,LC-1,AMA-M2,SLA/LP in all patients increased significantly.Among 57 AIH patients,the data of multiple subtypes were AIH-I in 38 cases,AIH II in 11 cases,and AIH III in 8 cases.ALT and AST levels in 23 PBC patients increased significantly.It shows that AIH patients with diff erent degrees of liver injury,ALT,AST significantly increased.The study found that the examination of autoantibodies and immune liver diseases can more accurately diagnose abnormal liver function,which has positive clinical significance.