血小板检验在早期诊断儿童川崎病中的价值研究

Study on the Value of Platelet Test in Early Diagnosis of Kawasaki Disease in Children

研究了血小板检验在早期诊断儿童川崎病中的价值。选择聊城市人民医院于2020年1月—2022年1月接诊的30例川崎病患儿(A组)作为研究对象,并选择同期体检健康的30例儿童(B组)进行对照。比较两组患儿的血小板检验指标。按照心脏彩超显示冠状动脉是否损伤,把A组患儿分为冠状动脉损伤组(CALs组)和非冠状动脉损伤组(非CALs组),然后根据美国心脏协会的iKD诊断标准将A组患儿分为完全川崎病和不完全川崎病组;并比较完全川崎病组(cKD组)和不完全川崎病组(iKD组)血小板检验指标。研究发现,川崎病患儿的PLT水平显著高于健康儿童,PDW、MPV水平显著低于健康儿童,在不完全川崎病患儿中的差异更加明显。所以,高水平的PLT、低水平的PDW、MPV可作为临床诊断不完全川崎病的指标,值得临床上应用及推广。

To study the value of platelet test in early diagnosis of Kawasaki disease in children.30 children with Kawasaki disease(Group A)who were admitted by Liaocheng People’s Hospital from January 2020 to January 2022 were selected as the study subjects,and 30 children(Group B)who were healthy in physical examination at the same time were selected as the control.The platelet test indexes of the two groups were compared.Group A was divided into coronary artery injury group(CALs group)and non-coronary artery injury group(non CALs group)according to whether the coronary artery was injured by color Doppler echocardiography;The platelet test indexes of complete Kawasaki disease(cKD group)and incomplete Kawasaki disease(iKD group)were compared.The study found that the PLT level of children with Kawasaki disease was significantly higher than that of healthy children,and the levels of PDW and MPV were significantly lower than those of healthy children.The difference was more obvious in children with incomplete Kawasaki disease.Therefore,high level PLT,low level PDW and MPV can be used as indicators for clinical diagnosis of incomplete Kawasaki disease,which is worthy of clinical application and promotion.