非霍奇金淋巴瘤患者癌症复发恐惧现状及影响因素研究

Fear of cancer recurrence and its influencing factors in patients with non-Hodgkin lymphoma

目的调查非霍奇金淋巴瘤(NHL)患者癌症复发恐惧(FCR)现状,分析其影响因素。方法采用一般资料调查表、恐惧疾病进展简化量表、社会支持量表、焦虑自评量表、抑郁自评量表、创伤后应激障碍检查表、简体中文版创伤后成长评定量表、疾病认知问卷、简易应对方式问卷及医患关系问卷对2021年5—12月上海交通大学医学院附属瑞金医院住院的264例NHL患者进行调查。结果NHL患者FCR得分为(30.69±9.13)分,有33.33%的患者(n=88)FCR≥34分;女性、居住在农村、在职、病程、疾病认知、应激水平、焦虑水平是FCR的影响因素(P<0.01)。结论约1/3的非霍奇金淋巴瘤患者存在病理水平的FCR,需要引起临床工作人员的高度重视;对于居住在农村、在职、病程在1年以内的女性,需要格外关注;可以通过认知行为疗法等干预措施,改变患者认知,降低患者的应激水平和焦虑水平,从而降低非霍奇金淋巴瘤患者FCR水平。

Objective To investigate the current situation of fear of cancer recurrence in patients with non-Hodgkin lymphoma and analyze its influencing factors.Methods A total of 264 patients with non-Hodgkin lymphoma who were admitted to Ruijin Hospital,Shanghai Jiao Tong University School of Medicine during May to December 2021 were selected.They were surveyed using the general data questionnaire,the Fear of Progression Questionnaire-Short Form(FOP-Q-SF),the Social Support Scale(SSRS),the Self-rating Anxiety Scale(SAS),the Self-rating Depression Scale(SDS),the PTSD Checklist(PCL),Chinese-Post Traumatic Growth Inventory(C-PTGI),the Brief Illness Perception Questionnaire(B-IPQ),the Simplified Coping Style Questionnaire(SCSQ),and the Doctor-PatientRelationship Questionnaire(PDRQ).Results The FCR score in NHL patients was(30.69±9.13),where 33.33%patients(n=88)had FCR≥34 scores.Female,living in rural areas,employment,course of disease,disease cognition,stress and anxiety were the influencing factors of FCR(P<0.01).Conclusions About 1/3 patients with non-Hodgkin lymphoma present pathological fear of cancer recurrence,which should be drawn much attention clinical staff.Special attention should be paid to women who live in rural areas,with employment and less than one year of disease course.Cognitive behavioral therapy and other interventions are suggested to change patient cognition,relieve stress and anxiety,so as to reduce the level of FCR in patients with non-Hodgkin lymphoma.