摘要
卵巢周围腹膜腔缺乏局部屏障,来源于卵泡液和腹腔积液等体液中的外泌体是卵巢癌肿瘤微环境中重要的非细胞成分。外泌体携带的内容物与其来源细胞高度相似,成为研究卵巢癌多种组织学类型所具有的独特生物学起源的新方向。文章就外泌体在卵巢上皮性癌多起源发生过程中的研究进展进行综述。
The periovarian peritoneal cavity lacks a local barrier,and exosomes derived from body fluids such as follicular fluid and ascites are important non‑cellular components in the tumor microenvironment of ovarian cancer.The contents carried by exosomes are highly similar to their source cells and become a new direction for studying the unique biological origin possessed by a variety of histological types of ovarian cancer.The article reviews the research progress of exosomes in the multiple origins of ovarian epithelial carcinoma.
作者
郝宇暾
Hao Yutun(Department of Gynecology,Heping Hospital Affiliated to Changzhi Medical College,Changzhi 046000,China)
出处
《肿瘤研究与临床》
CAS
2022年第12期950-953,共4页
Cancer Research and Clinic
关键词
卵巢肿瘤
卵巢上皮癌
外泌体
肿瘤微环境
Ovarian neoplasms
Carcinoma,ovarian epithelial
Exosome
Tumor microenvironment