外泌体参与卵巢上皮性癌多起源发生的研究进展

Progress of exosomes involved in multiple origins of ovarian epithelial carcinoma

卵巢周围腹膜腔缺乏局部屏障,来源于卵泡液和腹腔积液等体液中的外泌体是卵巢癌肿瘤微环境中重要的非细胞成分。外泌体携带的内容物与其来源细胞高度相似,成为研究卵巢癌多种组织学类型所具有的独特生物学起源的新方向。文章就外泌体在卵巢上皮性癌多起源发生过程中的研究进展进行综述。

The periovarian peritoneal cavity lacks a local barrier,and exosomes derived from body fluids such as follicular fluid and ascites are important non‑cellular components in the tumor microenvironment of ovarian cancer.The contents carried by exosomes are highly similar to their source cells and become a new direction for studying the unique biological origin possessed by a variety of histological types of ovarian cancer.The article reviews the research progress of exosomes in the multiple origins of ovarian epithelial carcinoma.