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柔性神经电极植入工具的振动植入参数研究

Study on vibration implantation parameters of flexible nerve electrode implantation tool
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摘要 为了分析振动植入中各振动参数对柔性神经电极辅助植入工具植入过程的影响,基于受迫振动及黏弹性材料的理论基础,通过运动学和黏弹性力学方法分析了振动中频率、振幅、振动波形对植入过程的影响;提出了穿刺能量这一植入过程评价指标,其更加直观反映被植入组织的损伤情况;最后,通过体外脑组织模型植入实验对理论分析结果进行了验证.实验结果表明:对各个振动参数影响的理论分析与实验结果基本相符,振动植入能降低植入中的穿刺力及穿刺能量,并且通过提高振幅及采用锯齿波进行触发,进一步降低植入过程的穿刺力及穿刺能量. In order to analyze the influence of vibration parameters on the implantation process of flexible nerve electrode assisted implantation tool,based on the theory of forced vibration and viscoelastic materials,the effects of frequency,amplitude and vibration waveform on the implantation process were analyzed by means of kinematics and viscoelastic mechanics.The evaluation method of penetration energy was put forward,which more intuitively reflected the damage of implanted tissue. Finally,the theory of brain implantation was verified by in vitro experiment.The experimental results show that the analysis of the influence of each vibration parameter in the theoretical part is basically consistent with the experimental results.Vibration implantation can effectively reduce the puncture force and puncture energy in the implantation process,and further reduce the puncture force and puncture energy in the implantation process by increasing the amplitude and triggering with sawtooth wave.
作者 胥浩天 张文光 贺雨欣 许李悦 XU Haotian;ZHANG Wenguang;HE Yuxin;XU Liyue(School of Mechanical Engineering,Shanghai Jiao Tong University,Shanghai 200240,China)
出处 《华中科技大学学报(自然科学版)》 EI CAS CSCD 北大核心 2022年第12期89-97,共9页 Journal of Huazhong University of Science and Technology(Natural Science Edition)
基金 国家自然科学基金资助项目(BC0200372)。
关键词 柔性神经电极 振动 穿刺力 穿刺能量 组织切割 flexible neural probe vibrations penetration force penetration energy tissue cutting
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