重氮化合物作为自由基前体参与的光催化反应

Photocatalytic Reactions Involving Diazo Compounds as Radical Precursors

重氮化合物作为一种用途广泛的合成子而备受化学家的青睐.在有机合成中,重氮化合物可以作为卡宾前体1,3-偶极子、C-亲核试剂、末端N-亲电试剂以及自由基中间体等.近年来,可见光催化重氮化合物产生自由基及其后续官能化反应取得了长足的进展.重点综述了近年来在可见光催化下,重氮化合物作为不同自由基前体参与的有机合成反应.主要包括光照产生重氮甲基自由基、碳自由基、卡拜自由基和联烯自由基等.最后对该领域未来的发展方向和面临的挑战做出了展望.

Diazo compounds are important synthons which have attracted condirable attentions by synthetic chemists.They can server as carbene precursors,1,3-dipoles,C-nucleophiles,terminal N-electrophiles and radical intermediates.In recent years,the photocatalytic generation of radicals from diazo compounds has made remarkable development.In this review,the recent developments in this research field are summarized which mainly focus on the generation of diazomethyl radical,carbon radicals,carbyne radicals and allene radicals from diazo compounds.Moreover,the future development direction,as well as challenges in this field is prospected.