高价碘试剂介导下的氧化重排反应

Oxidative Rearrangement Reactions Mediated by Hypervalent-Iodine Reagents

在过去的40年间,高价碘化学得到了迅猛发展,受到了广大有机合成工作者的广泛关注.高价碘试剂具有低毒、易制备、环境友好等优点,可以参与多种类型的氧化偶联、官能团化及重排等多种类型的反应;其中,就高价碘试剂参与的氧化重排反应而言,类型众多,常见的反应包C—X重排(X=C,N,O),X—C重排(X=N,O,S,Si,I),I—X重排(X=O,N)以及sigmatropic重排.对高价碘试剂参与的氧化重排反应进行了全面总结,以方便读者了解该领域的相关研究进展.

During the past 40 years,hypervalent-iodine chemistry has developed rapidly and extensive attention has been received from many organic researchers.For their advantages of low toxicity,easy preparation and environmental benignity,hypervalent iodine reagents have been widely applied in various types of organic transformation including oxidative coupling,functionalization,and rearrangement reactions.Among them,there exist a series of oxidative rearrangement reactions,which can be classified into many types including C to X migration(X=C,N or O),X to C migration(X=N,O,S,Si or I),I to X migration(X=O or N)and sigmatropic rearrangement.This review comprehensively summarizes the oxidative rearrangement reactions enabled by hypervalent iodine reagents,providing convenience for organic readers to learn the progress of this research field.