基于异喹啉骨架结构的新型聚集诱导发光分子的设计与合成

Design and Synthesis of Novel Aggregation-Induced Luminescence Molecules Based on Isoquinoline

聚集诱导发光(AIE)分子因其优异的光谱性能已广泛应用于化学、生物传感器、细胞成像和有机发光二极管(OLED)等研究领域.发现异喹啉并苯并噁嗪分子在高比例水/乙腈混合溶液中有着良好的荧光发射,呈现明显的AIE现象.在此基础上,继续设计、合成了一类融合四苯乙烯和异喹啉结构单元的新型AIE分子,研究发现该类分子亦具有良好的AIE现象.通过密度泛函理论(DFT)计算证实了两个结构单元的拼接有效地降低了前线轨道的能隙,有助于制备发射波长更长的荧光分子.该研究首次发现并制备了基于异喹啉结构的AIE分子,丰富了AIE家族成员.

Aggregation induced emission(AIE)molecules have been widely used in chemistry,biosensor,cell imaging and organic light-emitting diode(OLED)due to their excellent spectral properties.It was found for the first time that isoquinoline benzoxazine molecules exhibited good fluorescent emission in a high proportion of water/acetonitrile mixed solution,showing an obvious AIE phenomenon.On this basis,a novel type of AIE molecules fused with tetraphenylene and isoquinoline structural units were designed and synthesized.They were found exhibiting an excellent AIE phenomenon.It was confirmed by density functional theory(DFT)calculations that the splicing of the two structural units effectively reduced the energy gap of the frontier orbitals,which was helpful for the preparation of fluorescent molecules with longer emission wavelengths.In this study,AIE molecules based on the isoquinoline structure were discovered and prepared,which enriched the members of the AIE family.The AIE molecules based on the isoquinoline structure were first discovered and prepared in this study,which enriched the members of the AIE family.